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Response to Immune Checkpoint Inhibitors Is Affected by Deregulations in the Antigen Presentation Machinery: A Systematic Review and Meta-Analysis

Immune checkpoint inhibitors (ICI) targeting programmed death 1 (PD-1), its ligand (PD-L1), or cytotoxic T-lymphocyte antigen 4 (CTLA-4) have shown promising results against multiple cancers, where they reactivate exhausted T cells primed to eliminate tumor cells. ICI therapies have been particularl...

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Detalles Bibliográficos
Autores principales:	Rasmussen, Maria, Durhuus, Jon Ambæk, Nilbert, Mef, Andersen, Ove, Therkildsen, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821706/ https://www.ncbi.nlm.nih.gov/pubmed/36615128 http://dx.doi.org/10.3390/jcm12010329

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