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En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy
The aim of this study was to evaluate the choroidal vascularity analyzing en face optical coherence tomography (OCT) images in patients with unilateral central serous chorioretinopathy (CSC). We retrospectively evaluated 40 eyes of 20 CSC patients and 20 eyes of 10 gender- and age-matched healthy in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821730/ https://www.ncbi.nlm.nih.gov/pubmed/36614951 http://dx.doi.org/10.3390/jcm12010150 |
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author | Tatti, Filippo Iovino, Claudio Demarinis, Giuseppe Siotto Pintor, Emanuele Pellegrini, Marco Beale, Oliver Vupparaboina, Kiran Kumar Rasheed, Mohammed Abdul Giannaccare, Giuseppe Chhablani, Jay Peiretti, Enrico |
author_facet | Tatti, Filippo Iovino, Claudio Demarinis, Giuseppe Siotto Pintor, Emanuele Pellegrini, Marco Beale, Oliver Vupparaboina, Kiran Kumar Rasheed, Mohammed Abdul Giannaccare, Giuseppe Chhablani, Jay Peiretti, Enrico |
author_sort | Tatti, Filippo |
collection | PubMed |
description | The aim of this study was to evaluate the choroidal vascularity analyzing en face optical coherence tomography (OCT) images in patients with unilateral central serous chorioretinopathy (CSC). We retrospectively evaluated 40 eyes of 20 CSC patients and 20 eyes of 10 gender- and age-matched healthy individuals. The sample consisted of: (1) CSC affected eyes; (2) unaffected fellow eyes; (3) healthy eyes. Multiple cross-sectional enhanced depth imaging OCT scans were obtained to create a volume scan. En face scans of the whole choroid were obtained at 5μm intervals and were binarized to calculate the choroidal vascularity index (CVI). The latter, defined as the proportion of the luminal area to the total choroidal area, was calculated at the level of choriocapillaris, superficial, medium and deep layers. No significant differences between choriocapillaris, superficial, medium and deep CVI were found in both eyes of CSC patients, whereas a significant different trend of changes was found in healthy eyes. Nevertheless, the en face CVI shows no difference between affected fellow and healthy eyes. In conclusion, CSC-affected eyes and fellow eyes showed a similar vascular architecture, with no statistical difference between all choroidal layers. |
format | Online Article Text |
id | pubmed-9821730 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98217302023-01-07 En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy Tatti, Filippo Iovino, Claudio Demarinis, Giuseppe Siotto Pintor, Emanuele Pellegrini, Marco Beale, Oliver Vupparaboina, Kiran Kumar Rasheed, Mohammed Abdul Giannaccare, Giuseppe Chhablani, Jay Peiretti, Enrico J Clin Med Article The aim of this study was to evaluate the choroidal vascularity analyzing en face optical coherence tomography (OCT) images in patients with unilateral central serous chorioretinopathy (CSC). We retrospectively evaluated 40 eyes of 20 CSC patients and 20 eyes of 10 gender- and age-matched healthy individuals. The sample consisted of: (1) CSC affected eyes; (2) unaffected fellow eyes; (3) healthy eyes. Multiple cross-sectional enhanced depth imaging OCT scans were obtained to create a volume scan. En face scans of the whole choroid were obtained at 5μm intervals and were binarized to calculate the choroidal vascularity index (CVI). The latter, defined as the proportion of the luminal area to the total choroidal area, was calculated at the level of choriocapillaris, superficial, medium and deep layers. No significant differences between choriocapillaris, superficial, medium and deep CVI were found in both eyes of CSC patients, whereas a significant different trend of changes was found in healthy eyes. Nevertheless, the en face CVI shows no difference between affected fellow and healthy eyes. In conclusion, CSC-affected eyes and fellow eyes showed a similar vascular architecture, with no statistical difference between all choroidal layers. MDPI 2022-12-24 /pmc/articles/PMC9821730/ /pubmed/36614951 http://dx.doi.org/10.3390/jcm12010150 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tatti, Filippo Iovino, Claudio Demarinis, Giuseppe Siotto Pintor, Emanuele Pellegrini, Marco Beale, Oliver Vupparaboina, Kiran Kumar Rasheed, Mohammed Abdul Giannaccare, Giuseppe Chhablani, Jay Peiretti, Enrico En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy |
title | En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy |
title_full | En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy |
title_fullStr | En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy |
title_full_unstemmed | En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy |
title_short | En Face Choroidal Vascularity in Both Eyes of Patients with Unilateral Central Serous Chorioretinopathy |
title_sort | en face choroidal vascularity in both eyes of patients with unilateral central serous chorioretinopathy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821730/ https://www.ncbi.nlm.nih.gov/pubmed/36614951 http://dx.doi.org/10.3390/jcm12010150 |
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