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Alpha Ketoglutarate Downregulates the Neutral Endopeptidase and Enhances the Growth Inhibitory Activity of Thiorphan in Highly Aggressive Osteosarcoma Cells

Since natural substances are widely explored as epigenetic modulators of gene expression and epigenetic abnormalities are important causes of cancerogenesis, factors with pro-tumor activities subjected to epigenetic control, e.g., neutral endopeptidase (NEP, neprilysin), are promising anticancer tar...

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Detalles Bibliográficos
Autores principales:	Mizerska-Kowalska, Magdalena, Sławińska-Brych, Adrianna, Niedziela, Emilia, Brodovskiy, Viktor, Zdzisińska, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821816/ https://www.ncbi.nlm.nih.gov/pubmed/36615293 http://dx.doi.org/10.3390/molecules28010097

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