Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells

Utilization of specific codons varies between organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons are frequently mutated to other codons. Moreover, arginine limita...

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Detalles Bibliográficos
Autores principales: Hsu, Dennis J., Gao, Jenny, Yamaguchi, Norihiro, Pinzaru, Alexandra, Wu, Qiushuang, Mandayam, Nandan, Liberti, Maria, Heissel, Søren, Alwaseem, Hanan, Tavazoie, Saeed, Tavazoie, Sohail F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821863/
https://www.ncbi.nlm.nih.gov/pubmed/36608131
http://dx.doi.org/10.1126/sciadv.ade9120

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