Cargando…

Biological Activity of Amidino-Substituted Imidazo [4,5-b]pyridines

A series of cyano- and amidino-substituted imidazo[4,5-b]pyridines were synthesized using standard methods of organic synthesis, and their biological activity was evaluated. Biological evaluation included in vitro assessment of antiproliferative effects on a diverse selection of human cancer cell li...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pavlinac, Ida Boček, Zlatić, Katarina, Persoons, Leentje, Daelemans, Dirk, Banjanac, Mihajlo, Radovanović, Vedrana, Butković, Kristina, Kralj, Marijeta, Hranjec, Marijana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822021/ https://www.ncbi.nlm.nih.gov/pubmed/36615231 http://dx.doi.org/10.3390/molecules28010034

Ejemplares similares

Synthesis and Antiproliferative Activity of 2,6-Disubstituted Imidazo[4,5-b]pyridines Prepared by Suzuki Cross Coupling
por: Boček Pavlinac, Ida, et al.
Publicado: (2023)

Novel Biologically Active N-Substituted Benzimidazole Derived Schiff Bases: Design, Synthesis, and Biological Evaluation
por: Beč, Anja, et al.
Publicado: (2023)

Experimental and Computational Study of the Antioxidative Potential of Novel Nitro and Amino Substituted Benzimidazole/Benzothiazole-2-Carboxamides with Antiproliferative Activity
por: Cindrić, Maja, et al.
Publicado: (2019)

Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles
por: Racané, Livio, et al.
Publicado: (2021)

Synthesis, Computational Analysis, and Antiproliferative Activity of Novel Benzimidazole Acrylonitriles as Tubulin Polymerization Inhibitors: Part 2
por: Beč, Anja, et al.
Publicado: (2021)

Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives
por: Krause, Malwina, et al.
Publicado: (2017)

Biological Activity of Newly Synthesized Benzimidazole and Benzothizole 2,5-Disubstituted Furane Derivatives
por: Racané, Livio, et al.
Publicado: (2021)

Design, synthesis, biological evaluation and QSAR analysis of novel N-substituted benzimidazole derived carboxamides
por: Beč, Anja, et al.
Publicado: (2022)

A Simple Precursor for Highly Functionalized Fused Imidazo[4,5-b]pyridines and Imidazo[4,5-b]-1,8-naphthyridine
por: Al-duaij, Omar K., et al.
Publicado: (2016)

Synthesis, Antiproliferative Evaluation and QSAR Analysis of Novel Halogen- and Amidino-Substituted Benzothiazoles and Benzimidazoles
por: Rep Kaulić, Valentina, et al.
Publicado: (2022)

Synthesis and Thrombin, Factor Xa and U46619 Inhibitory Effects of Non-Amidino and Amidino N(2)-Thiophenecarbonyl- and N(2)-Tosylanthranilamides
por: Lee, Soo Hyun, et al.
Publicado: (2017)

Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles
por: Racané, Livio, et al.
Publicado: (2021)

Formation and structural characterization of a potassium amidinoguanidinate
por: Lorenz, Volker, et al.
Publicado: (2018)

6-Bromo-3-methyl-2-phenyl-3H-imidazo[4,5-b]pyridine
por: Ouzidan, Younes, et al.
Publicado: (2011)

4-Benzyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine
por: Ouzidan, Y., et al.
Publicado: (2010)

Exploring the excited state behavior for 2-(phenyl)imidazo[4,5-c]pyridine in methanol solvent
por: Yang, Dapeng, et al.
Publicado: (2017)

4-Allyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine monohydrate
por: Ouzidan, Younès, et al.
Publicado: (2010)

Exploring Antimicrobial Features for New Imidazo[4,5-b]pyridine Derivatives Based on Experimental and Theoretical Study
por: Hjouji, Mohammed-yassin, et al.
Publicado: (2023)

Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds
por: Carivenc, Coralie, et al.
Publicado: (2021)

4-Amidinopyridinium hexachloridostannate(IV) dihydrate
por: Ghallab, Rochdi, et al.
Publicado: (2022)

Design and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2H-Benzo[g]indazole Derivatives: Antiproliferative and Antibacterial Activity
por: Cuartas, Viviana, et al.
Publicado: (2019)

3-Ethyl-5-(4-methoxyphenoxy)-2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridine
por: Ranjith, S., et al.
Publicado: (2011)

1-Acetyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Dahmani, Siham, et al.
Publicado: (2011)

3-Allyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Dahmani, Siham, et al.
Publicado: (2011)

6-Bromo-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Ghacham, Hend Bel, et al.
Publicado: (2010)

3-Benzyl-6-bromo-2-(2-furyl)-3H-imidazo[4,5-b]pyridine
por: Ouzidan, Younès, et al.
Publicado: (2010)

3-Benzyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Kandri Rodi, Youssef, et al.
Publicado: (2013)

Crystal structure of 4-bromo-2-(1H-imidazo[4,5-b]pyridin-2-yl)phenol
por: Ouari, Kamel
Publicado: (2015)

Detection of 2‐Amino‐1‐methyl‐6‐(4‐hydroxyphenyl)imidazo[4,5‐b]pyridine in Broiled Beef
por: Kurosaka, Reiko, et al.
Publicado: (1992)

Formation and structure of the first metal complexes comprising amidinoguanidinate ligands
por: Sroor, Farid M., et al.
Publicado: (2016)

Synthesis and in Vitro and in Vivo Anticoagulant and Antiplatelet Activities of Amidino- and Non-Amidinobenzamides
por: Lee, Soo Hyun, et al.
Publicado: (2016)

Preparation of Antiproliferative Terpene-Alkaloid Hybrids by Free Radical-Mediated Modification of ent-Kauranic Derivatives
por: Pruteanu, Elena, et al.
Publicado: (2021)

tert-Butyl N-(5-bromo-1H-imidazo[4,5-b]pyridin-2-ylmethyl)carbamate
por: Yin, Ling, et al.
Publicado: (2008)

1,3-Diallyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Dahmani, Siham, et al.
Publicado: (2011)

1,3-Dibenzyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Dahmani, S., et al.
Publicado: (2010)

6-Bromo-1,3-dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
por: Dahmani, Siham, et al.
Publicado: (2010)

2-(5,6-Dibromo-7-methyl-3H-imidazo[4,5-b]pyridin-2-yl)phenol
por: Wang, Haixia
Publicado: (2010)

N-(6-Chloro-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)benzenesulfonamide
por: Devaru, Venkatesh B., et al.
Publicado: (2014)

2,3-Diaryl-3H-imidazo[4,5-b]pyridine derivatives as potential anticancer and anti-inflammatory agents
por: Marie Kirwen, Erin, et al.
Publicado: (2017)

Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma
por: Zhang, Lishun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ju5u00simk6oq8epj8q5pmq0b9