Cargando…

Limited efficacy of repeated praziquantel treatment in Schistosoma mansoni infections as revealed by highly accurate diagnostics, PCR and UCP-LF CAA (RePST trial)

BACKGROUND: Most studies assessing praziquantel (PZQ) efficacy have used relatively insensitive diagnostic methods, thereby overestimating cure rate (CR) and intensity reduction rate (IRR). To determine accurately PZQ efficacy, we employed more sensitive DNA and circulating antigen detection methods...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoekstra, Pytsje T., Casacuberta-Partal, Miriam, van Lieshout, Lisette, Corstjens, Paul L. A. M., Tsonaka, Roula, Assaré, Rufin K., Silué, Kigbafori D., N’Goran, Eliézer K., N’Gbesso, Yves K., Brienen, Eric A. T., Roestenberg, Meta, Knopp, Stefanie, Utzinger, Jürg, Coulibaly, Jean T., van Dam, Govert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822103/ https://www.ncbi.nlm.nih.gov/pubmed/36548444 http://dx.doi.org/10.1371/journal.pntd.0011008

Ejemplares similares

Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST)
por: Hoekstra, Pytsje T., et al.
Publicado: (2020)

Repeated doses of Praziquantel in Schistosomiasis Treatment (RePST) – single versus multiple praziquantel treatments in school-aged children in Côte d’Ivoire: a study protocol for an open-label, randomised controlled trial
por: Hoekstra, P. T., et al.
Publicado: (2018)

Utilizing the ultrasensitive Schistosoma up-converting phosphor lateral flow circulating anodic antigen (UCP-LF CAA) assay for sample pooling-strategies
por: Corstjens, Paul L. A. M., et al.
Publicado: (2017)

Accuracy of Urine Circulating Cathodic Antigen Test for the Diagnosis of Schistosoma mansoni in Preschool-Aged Children before and after Treatment
por: Coulibaly, Jean T., et al.
Publicado: (2013)

Excretion patterns of Schistosoma mansoni antigens CCA and CAA by adult male and female worms, using a mouse model and ex vivo parasite cultures
por: Casacuberta-Partal, Miriam, et al.
Publicado: (2022)

Diagnosis of Schistosomiasis without a Microscope: Evaluating Circulating Antigen (CCA, CAA) and DNA Detection Methods on Banked Samples of a Community-Based Survey from DR Congo
por: Hoekstra, Pytsje T., et al.
Publicado: (2022)

Accuracy of Urine Circulating Cathodic Antigen (CCA) Test for Schistosoma mansoni Diagnosis in Different Settings of Côte d'Ivoire
por: Coulibaly, Jean T., et al.
Publicado: (2011)

Evaluation of microscopy, serology, circulating anodic antigen (CAA), and eosinophil counts for the follow-up of migrants with chronic schistosomiasis: a prospective cohort study
por: Tamarozzi, Francesca, et al.
Publicado: (2021)

Accuracy of Two Circulating Antigen Tests for the Diagnosis and Surveillance of Schistosoma mansoni Infection in Low-Endemicity Settings of Côte d’Ivoire
por: Assaré, Rufin K., et al.
Publicado: (2021)

Efficacy and Safety of Praziquantel in Preschool-Aged Children in an Area Co-Endemic for Schistosoma mansoni and S. haematobium
por: Coulibaly, Jean T., et al.
Publicado: (2012)

Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes
por: Corstjens, Paul LAM, et al.
Publicado: (2015)

In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats
por: Figura, Grzegorz, et al.
Publicado: (2015)

Prospective, observational study to assess the performance of CAA measurement as a diagnostic tool for the detection of Schistosoma haematobium infections in pregnant women and their child in Lambaréné, Gabon: study protocol of the freeBILy clinical trial in Gabon
por: Honkpehedji, Yabo Josiane, et al.
Publicado: (2020)

Subclinical signs of podocyte injury associated with Circulating Anodic Antigen (CAA) in Schistosoma mansoni-infected patients in Brazil
por: Sousa, Mariana Silva, et al.
Publicado: (2023)

Improved diagnosis of active Schistosoma infection in travellers and migrants using the ultra-sensitive in-house lateral flow test for detection of circulating anodic antigen (CAA) in serum
por: van Grootveld, Rebecca, et al.
Publicado: (2018)

Sensitivity of the Point-of-Care Circulating Cathodic Antigen Urine Cassette Test for Diagnosis of Schistosoma mansoni in Low-Endemicity Settings in Côte d’Ivoire
por: Assaré, Rufin K., et al.
Publicado: (2018)

Spatially-explicit risk profiling of Plasmodium falciparum infections at a small scale: a geostatistical modelling approach
por: Silué, Kigbafori D, et al.
Publicado: (2008)

Performance of an Ultra-Sensitive Assay Targeting the Circulating Anodic Antigen (CAA) for Detection of Schistosoma mansoni Infection in a Low Endemic Area in Brazil
por: Sousa, Mariana Silva, et al.
Publicado: (2019)

Rare forms of cerebral amyloid angiopathy: pathogenesis, biological and clinical features of CAA-ri and iCAA
por: Storti, Benedetta, et al.
Publicado: (2023)

Intestinal parasitic infections in schoolchildren in different settings of Côte d’Ivoire: effect of diagnostic approach and implications for control
por: Coulibaly, Jean T, et al.
Publicado: (2012)

Praziquantel, Mefloquine-Praziquantel, and Mefloquine-Artesunate-Praziquantel against Schistosoma haematobium: A Randomized, Exploratory, Open-Label Trial
por: Keiser, Jennifer, et al.
Publicado: (2014)

Spatial risk profiling of Plasmodium falciparum parasitaemia in a high endemicity area in Côte d'Ivoire
por: Raso, Giovanna, et al.
Publicado: (2009)

Circulating Anodic Antigen (CAA): A Highly Sensitive Diagnostic Biomarker to Detect Active Schistosoma Infections—Improvement and Use during SCORE
por: Corstjens, Paul L. A. M., et al.
Publicado: (2020)

Sensitive Diagnosis and Post-Treatment Follow-Up of Schistosoma mansoni Infections in Asymptomatic Eritrean Refugees by Circulating Anodic Antigen Detection and Polymerase Chain Reaction
por: Hoekstra, Pytsje T., et al.
Publicado: (2022)

Schistosomiasis, Soil-Transmitted Helminthiasis, and Sociodemographic Factors Influence Quality of Life of Adults in Côte d'Ivoire
por: Fürst, Thomas, et al.
Publicado: (2012)

Sentimental study of CAA by location-based tweets
por: Vashisht, Geetika, et al.
Publicado: (2021)

Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among Preschool-Aged Children in Blapleu, Biankouma District, Western Côte d'Ivoire
por: N'Zi, Constant Konan, et al.
Publicado: (2021)

Efficacy and Safety of Albendazole in Hookworm-infected Preschool-aged Children, School-aged Children, and Adults in Côte d’Ivoire: A Phase 2 Randomized, Controlled Dose-finding Trial
por: Patel, Chandni, et al.
Publicado: (2020)

Scope and Limits of an Anamnestic Questionnaire in a Control-Induced Low-Endemicity Helminthiasis Setting in South-Central Côte d’Ivoire
por: Fürst, Thomas, et al.
Publicado: (2013)

Diagnosis, Clinical Features, and Self-Reported Morbidity of Strongyloides stercoralis and Hookworm Infection in a Co-Endemic Setting
por: Becker, Sören L., et al.
Publicado: (2011)

Genetic diversity of Plasmodium falciparum among school-aged children from the Man region, western Côte d’Ivoire
por: Mara, Sarah E, et al.
Publicado: (2013)

Concomitant Plasmodium falciparum and intestinal helminth infections in a rural community of southern Côte d’lvoire
por: Yapi, Richard B, et al.
Publicado: (2012)

Mechanisms Underlying the Virulence Regulation of Vibrio alginolyticus ND-01 pstS and pstB with a Transcriptomic Analysis
por: Yi, Xin, et al.
Publicado: (2022)

Efficacy and safety of ascending dosages of albendazole against Trichuris trichiura in preschool-aged children, school-aged children and adults: A multi-cohort randomized controlled trial
por: Patel, Chandni, et al.
Publicado: (2020)

Comparing Diagnostic Accuracy of Kato-Katz, Koga Agar Plate, Ether-Concentration, and FLOTAC for Schistosoma mansoni and Soil-Transmitted Helminths
por: Glinz, Dominik, et al.
Publicado: (2010)

Counteraction of inflammatory activity in CAA-related subarachnoid hemorrhage
por: Schreiber, Stefanie, et al.
Publicado: (2022)

Antigen-based diagnosis of Schistosoma infection in travellers: a prospective study
por: Casacuberta-Partal, Miriam, et al.
Publicado: (2020)

Evaluation of the implementation of hospital hygiene components in 30 health-care facilities in the autonomous district of Abidjan (Cote d’Ivoire) with the WHO Infection Prevention and Control Assessment Framework (IPCAF)
por: Cissé, Doumbia Mariamou, et al.
Publicado: (2023)

Prevalence of Schistosoma mono- and co-infections with multiple common parasites and associated risk factors and morbidity profile among adults in the Taabo health and demographic surveillance system, South-Central Côte d’Ivoire
por: Bassa, Fidèle K., et al.
Publicado: (2022)

Efficacy and safety of ascending doses of praziquantel against Schistosoma haematobium infection in preschool-aged and school-aged children: a single-blind randomised controlled trial
por: Coulibaly, Jean T., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_fu0bja1865a9alm66umjj943dc