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Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures

The aim of the research presented in this paper was to determine the effect of dihydroxy alcohols on the rheological properties of sodium carboxymethylcellulose (Na-CMC) solutions with different degrees of substitution and different average molecular masses. Rheological measurements were carried out...

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Autores principales: Wagner, Patrycja, Różańska, Sylwia, Warmbier, Ewelina, Frankiewicz, Adrianna, Różański, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822266/
https://www.ncbi.nlm.nih.gov/pubmed/36614757
http://dx.doi.org/10.3390/ma16010418
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author Wagner, Patrycja
Różańska, Sylwia
Warmbier, Ewelina
Frankiewicz, Adrianna
Różański, Jacek
author_facet Wagner, Patrycja
Różańska, Sylwia
Warmbier, Ewelina
Frankiewicz, Adrianna
Różański, Jacek
author_sort Wagner, Patrycja
collection PubMed
description The aim of the research presented in this paper was to determine the effect of dihydroxy alcohols on the rheological properties of sodium carboxymethylcellulose (Na-CMC) solutions with different degrees of substitution and different average molecular masses. Rheological measurements were carried out with a rotational rheometer in continuous and oscillatory flows. Two dihydroxy alcohols were used in the study: butane-1,3-diol and propane-1,2-diol. The concentration of Na-CMC in the solutions was 1.6% and 2.2%, while the concentration of the dihydroxy alcohols ranged from 10% to 60%. The measurements show that the viscoelastic properties of Na-CMC solutions are strongly linked to the type of solvent used. The application of low-substituted high-molecular-mass Na-CMC makes it possible to obtain fluids with the properties of weak physical gels. On the other hand, the dissolution of Na-CMC with a high degree of substitution (>1) and low molecular mass in dihydroxy alcohol/water mixtures yields a viscoelastic fluid. Based on oscillatory measurements, increasing concentrations of polyhydroxy alcohols in Na-CMC solutions were found to induce an increase in the strength of the network structure. At the same concentrations of polyhydroxy alcohols in solutions containing butane-1,3-diol, a stronger network structure is formed compared to solutions containing propane-1,2-diol. The rheological measurement results presented in this paper may be useful in the formulation of drug carriers and cosmetics in which rheological properties are a significant factor.
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spelling pubmed-98222662023-01-07 Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures Wagner, Patrycja Różańska, Sylwia Warmbier, Ewelina Frankiewicz, Adrianna Różański, Jacek Materials (Basel) Article The aim of the research presented in this paper was to determine the effect of dihydroxy alcohols on the rheological properties of sodium carboxymethylcellulose (Na-CMC) solutions with different degrees of substitution and different average molecular masses. Rheological measurements were carried out with a rotational rheometer in continuous and oscillatory flows. Two dihydroxy alcohols were used in the study: butane-1,3-diol and propane-1,2-diol. The concentration of Na-CMC in the solutions was 1.6% and 2.2%, while the concentration of the dihydroxy alcohols ranged from 10% to 60%. The measurements show that the viscoelastic properties of Na-CMC solutions are strongly linked to the type of solvent used. The application of low-substituted high-molecular-mass Na-CMC makes it possible to obtain fluids with the properties of weak physical gels. On the other hand, the dissolution of Na-CMC with a high degree of substitution (>1) and low molecular mass in dihydroxy alcohol/water mixtures yields a viscoelastic fluid. Based on oscillatory measurements, increasing concentrations of polyhydroxy alcohols in Na-CMC solutions were found to induce an increase in the strength of the network structure. At the same concentrations of polyhydroxy alcohols in solutions containing butane-1,3-diol, a stronger network structure is formed compared to solutions containing propane-1,2-diol. The rheological measurement results presented in this paper may be useful in the formulation of drug carriers and cosmetics in which rheological properties are a significant factor. MDPI 2023-01-02 /pmc/articles/PMC9822266/ /pubmed/36614757 http://dx.doi.org/10.3390/ma16010418 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wagner, Patrycja
Różańska, Sylwia
Warmbier, Ewelina
Frankiewicz, Adrianna
Różański, Jacek
Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures
title Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures
title_full Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures
title_fullStr Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures
title_full_unstemmed Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures
title_short Rheological Properties of Sodium Carboxymethylcellulose Solutions in Dihydroxy Alcohol/Water Mixtures
title_sort rheological properties of sodium carboxymethylcellulose solutions in dihydroxy alcohol/water mixtures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822266/
https://www.ncbi.nlm.nih.gov/pubmed/36614757
http://dx.doi.org/10.3390/ma16010418
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