Ameliorative Effect of Structurally Divergent Oleanane Triterpenoid, 3-Epifriedelinol from Ipomoea batatas against BPA-Induced Gonadotoxicity by Targeting PARP and NF-κB Signaling in Rats

The pentacyclic triterpenoids (PTs) of plant origin are reputed to restrain prostate cancer (PCa) cell proliferation. This study aims to assess 3-epifriedelinol (EFD) isolated from aerial part of Ipomoea batatas against PCa and its potential mechanism, in vitro and in vivo. Molecular docking affirms...

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Detalles Bibliográficos
Autores principales: Majid, Muhammad, Farhan, Anam, Baig, Muhammad Waleed, Khan, Muhammad Tariq, Kamal, Yousaf, Hassan, Syed Shams ul, Bungau, Simona, Haq, Ihsan-ul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822353/
https://www.ncbi.nlm.nih.gov/pubmed/36615482
http://dx.doi.org/10.3390/molecules28010290

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