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Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis
The abuse and residues of antibiotics have a great impact on the environment and organisms, and their determination has become very important. Due to their low contents, varieties and complex matrices, effective recognition, separation and enrichment are usually required prior to determination. Mole...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822428/ https://www.ncbi.nlm.nih.gov/pubmed/36615529 http://dx.doi.org/10.3390/molecules28010335 |
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author | Zhao, Guangli Zhang, Yue Sun, Dani Yan, Shili Wen, Yuhao Wang, Yixiao Li, Guisheng Liu, Huitao Li, Jinhua Song, Zhihua |
author_facet | Zhao, Guangli Zhang, Yue Sun, Dani Yan, Shili Wen, Yuhao Wang, Yixiao Li, Guisheng Liu, Huitao Li, Jinhua Song, Zhihua |
author_sort | Zhao, Guangli |
collection | PubMed |
description | The abuse and residues of antibiotics have a great impact on the environment and organisms, and their determination has become very important. Due to their low contents, varieties and complex matrices, effective recognition, separation and enrichment are usually required prior to determination. Molecularly imprinted polymers (MIPs), a kind of highly selective polymer prepared via molecular imprinting technology (MIT), are used widely in the analytical detection of antibiotics, as adsorbents of solid-phase extraction (SPE) and as recognition elements of sensors. Herein, recent advances in MIPs for antibiotic residue analysis are reviewed. Firstly, several new preparation techniques of MIPs for detecting antibiotics are briefly introduced, including surface imprinting, nanoimprinting, living/controlled radical polymerization, and multi-template imprinting, multi-functional monomer imprinting and dummy template imprinting. Secondly, several SPE modes based on MIPs are summarized, namely packed SPE, magnetic SPE, dispersive SPE, matrix solid-phase dispersive extraction, solid-phase microextraction, stir-bar sorptive extraction and pipette-tip SPE. Thirdly, the basic principles of MIP-based sensors and three sensing modes, including electrochemical sensing, optical sensing and mass sensing, are also outlined. Fourthly, the research progress on molecularly imprinted SPEs (MISPEs) and MIP-based electrochemical/optical/mass sensors for the detection of various antibiotic residues in environmental and food samples since 2018 are comprehensively reviewed, including sulfonamides, quinolones, β-lactams and so on. Finally, the preparation and application prospects of MIPs for detecting antibiotics are outlined. |
format | Online Article Text |
id | pubmed-9822428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98224282023-01-07 Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis Zhao, Guangli Zhang, Yue Sun, Dani Yan, Shili Wen, Yuhao Wang, Yixiao Li, Guisheng Liu, Huitao Li, Jinhua Song, Zhihua Molecules Review The abuse and residues of antibiotics have a great impact on the environment and organisms, and their determination has become very important. Due to their low contents, varieties and complex matrices, effective recognition, separation and enrichment are usually required prior to determination. Molecularly imprinted polymers (MIPs), a kind of highly selective polymer prepared via molecular imprinting technology (MIT), are used widely in the analytical detection of antibiotics, as adsorbents of solid-phase extraction (SPE) and as recognition elements of sensors. Herein, recent advances in MIPs for antibiotic residue analysis are reviewed. Firstly, several new preparation techniques of MIPs for detecting antibiotics are briefly introduced, including surface imprinting, nanoimprinting, living/controlled radical polymerization, and multi-template imprinting, multi-functional monomer imprinting and dummy template imprinting. Secondly, several SPE modes based on MIPs are summarized, namely packed SPE, magnetic SPE, dispersive SPE, matrix solid-phase dispersive extraction, solid-phase microextraction, stir-bar sorptive extraction and pipette-tip SPE. Thirdly, the basic principles of MIP-based sensors and three sensing modes, including electrochemical sensing, optical sensing and mass sensing, are also outlined. Fourthly, the research progress on molecularly imprinted SPEs (MISPEs) and MIP-based electrochemical/optical/mass sensors for the detection of various antibiotic residues in environmental and food samples since 2018 are comprehensively reviewed, including sulfonamides, quinolones, β-lactams and so on. Finally, the preparation and application prospects of MIPs for detecting antibiotics are outlined. MDPI 2023-01-01 /pmc/articles/PMC9822428/ /pubmed/36615529 http://dx.doi.org/10.3390/molecules28010335 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhao, Guangli Zhang, Yue Sun, Dani Yan, Shili Wen, Yuhao Wang, Yixiao Li, Guisheng Liu, Huitao Li, Jinhua Song, Zhihua Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis |
title | Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis |
title_full | Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis |
title_fullStr | Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis |
title_full_unstemmed | Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis |
title_short | Recent Advances in Molecularly Imprinted Polymers for Antibiotic Analysis |
title_sort | recent advances in molecularly imprinted polymers for antibiotic analysis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822428/ https://www.ncbi.nlm.nih.gov/pubmed/36615529 http://dx.doi.org/10.3390/molecules28010335 |
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