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High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar

Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016. Methodology: Fecal immunochemical testing (FIT) was...

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Autores principales: John, Anil K, Varughese, Betsy, Abushaikha, Shaikha S, Hamdan, Ahed M, Pillai, Viswapriya, Ayash, Ahmad M, Vincent, Paul K, Sultan, Khaleel, Al Ejji, Khalid M, Singh, Rajvir, Alabdulla, Samya, Abdulmalik, Mariam, Al Kaabi, Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822526/
https://www.ncbi.nlm.nih.gov/pubmed/36628034
http://dx.doi.org/10.7759/cureus.32274
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author John, Anil K
Varughese, Betsy
Abushaikha, Shaikha S
Hamdan, Ahed M
Pillai, Viswapriya
Ayash, Ahmad M
Vincent, Paul K
Sultan, Khaleel
Al Ejji, Khalid M
Singh, Rajvir
Alabdulla, Samya
Abdulmalik, Mariam
Al Kaabi, Saad
author_facet John, Anil K
Varughese, Betsy
Abushaikha, Shaikha S
Hamdan, Ahed M
Pillai, Viswapriya
Ayash, Ahmad M
Vincent, Paul K
Sultan, Khaleel
Al Ejji, Khalid M
Singh, Rajvir
Alabdulla, Samya
Abdulmalik, Mariam
Al Kaabi, Saad
author_sort John, Anil K
collection PubMed
description Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016. Methodology: Fecal immunochemical testing (FIT) was used for average-risk individuals aged 50 to 74 years. Fecal immunochemical testing -positive participants were referred for total colonoscopy to detect polyps and cancers. Results: Among 32,751 FIT invitees, 11,130 took the test, and 758 (6%) of those were FIT positive. Of these, 375 (56.13%) participants underwent a colonoscopy, and polyps were detected in 198 (52.8%) and cancers in 19 (5.1%) participants. The adenoma detection rate exceeded 40%. Discussion and conclusion: The high yield of polyps and cancers in the screening program justifies an active, resource-intensive, and organized bowel cancer screening effort. The high adenoma detection rate in a FIT-based program warrants recalibration of target adenoma detection rates in screening programs.
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spelling pubmed-98225262023-01-09 High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar John, Anil K Varughese, Betsy Abushaikha, Shaikha S Hamdan, Ahed M Pillai, Viswapriya Ayash, Ahmad M Vincent, Paul K Sultan, Khaleel Al Ejji, Khalid M Singh, Rajvir Alabdulla, Samya Abdulmalik, Mariam Al Kaabi, Saad Cureus Gastroenterology Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016. Methodology: Fecal immunochemical testing (FIT) was used for average-risk individuals aged 50 to 74 years. Fecal immunochemical testing -positive participants were referred for total colonoscopy to detect polyps and cancers. Results: Among 32,751 FIT invitees, 11,130 took the test, and 758 (6%) of those were FIT positive. Of these, 375 (56.13%) participants underwent a colonoscopy, and polyps were detected in 198 (52.8%) and cancers in 19 (5.1%) participants. The adenoma detection rate exceeded 40%. Discussion and conclusion: The high yield of polyps and cancers in the screening program justifies an active, resource-intensive, and organized bowel cancer screening effort. The high adenoma detection rate in a FIT-based program warrants recalibration of target adenoma detection rates in screening programs. Cureus 2022-12-06 /pmc/articles/PMC9822526/ /pubmed/36628034 http://dx.doi.org/10.7759/cureus.32274 Text en Copyright © 2022, John et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
John, Anil K
Varughese, Betsy
Abushaikha, Shaikha S
Hamdan, Ahed M
Pillai, Viswapriya
Ayash, Ahmad M
Vincent, Paul K
Sultan, Khaleel
Al Ejji, Khalid M
Singh, Rajvir
Alabdulla, Samya
Abdulmalik, Mariam
Al Kaabi, Saad
High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
title High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
title_full High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
title_fullStr High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
title_full_unstemmed High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
title_short High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
title_sort high adenoma detection rates in fecal immunochemical test-based colorectal cancer screening: interim results of the national bowel cancer screening program in qatar
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822526/
https://www.ncbi.nlm.nih.gov/pubmed/36628034
http://dx.doi.org/10.7759/cureus.32274
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