Cargando…
High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar
Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016. Methodology: Fecal immunochemical testing (FIT) was...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822526/ https://www.ncbi.nlm.nih.gov/pubmed/36628034 http://dx.doi.org/10.7759/cureus.32274 |
_version_ | 1784865967663218688 |
---|---|
author | John, Anil K Varughese, Betsy Abushaikha, Shaikha S Hamdan, Ahed M Pillai, Viswapriya Ayash, Ahmad M Vincent, Paul K Sultan, Khaleel Al Ejji, Khalid M Singh, Rajvir Alabdulla, Samya Abdulmalik, Mariam Al Kaabi, Saad |
author_facet | John, Anil K Varughese, Betsy Abushaikha, Shaikha S Hamdan, Ahed M Pillai, Viswapriya Ayash, Ahmad M Vincent, Paul K Sultan, Khaleel Al Ejji, Khalid M Singh, Rajvir Alabdulla, Samya Abdulmalik, Mariam Al Kaabi, Saad |
author_sort | John, Anil K |
collection | PubMed |
description | Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016. Methodology: Fecal immunochemical testing (FIT) was used for average-risk individuals aged 50 to 74 years. Fecal immunochemical testing -positive participants were referred for total colonoscopy to detect polyps and cancers. Results: Among 32,751 FIT invitees, 11,130 took the test, and 758 (6%) of those were FIT positive. Of these, 375 (56.13%) participants underwent a colonoscopy, and polyps were detected in 198 (52.8%) and cancers in 19 (5.1%) participants. The adenoma detection rate exceeded 40%. Discussion and conclusion: The high yield of polyps and cancers in the screening program justifies an active, resource-intensive, and organized bowel cancer screening effort. The high adenoma detection rate in a FIT-based program warrants recalibration of target adenoma detection rates in screening programs. |
format | Online Article Text |
id | pubmed-9822526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-98225262023-01-09 High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar John, Anil K Varughese, Betsy Abushaikha, Shaikha S Hamdan, Ahed M Pillai, Viswapriya Ayash, Ahmad M Vincent, Paul K Sultan, Khaleel Al Ejji, Khalid M Singh, Rajvir Alabdulla, Samya Abdulmalik, Mariam Al Kaabi, Saad Cureus Gastroenterology Introduction: Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016. Methodology: Fecal immunochemical testing (FIT) was used for average-risk individuals aged 50 to 74 years. Fecal immunochemical testing -positive participants were referred for total colonoscopy to detect polyps and cancers. Results: Among 32,751 FIT invitees, 11,130 took the test, and 758 (6%) of those were FIT positive. Of these, 375 (56.13%) participants underwent a colonoscopy, and polyps were detected in 198 (52.8%) and cancers in 19 (5.1%) participants. The adenoma detection rate exceeded 40%. Discussion and conclusion: The high yield of polyps and cancers in the screening program justifies an active, resource-intensive, and organized bowel cancer screening effort. The high adenoma detection rate in a FIT-based program warrants recalibration of target adenoma detection rates in screening programs. Cureus 2022-12-06 /pmc/articles/PMC9822526/ /pubmed/36628034 http://dx.doi.org/10.7759/cureus.32274 Text en Copyright © 2022, John et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Gastroenterology John, Anil K Varughese, Betsy Abushaikha, Shaikha S Hamdan, Ahed M Pillai, Viswapriya Ayash, Ahmad M Vincent, Paul K Sultan, Khaleel Al Ejji, Khalid M Singh, Rajvir Alabdulla, Samya Abdulmalik, Mariam Al Kaabi, Saad High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar |
title | High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar |
title_full | High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar |
title_fullStr | High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar |
title_full_unstemmed | High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar |
title_short | High Adenoma Detection Rates in Fecal Immunochemical Test-Based Colorectal Cancer Screening: Interim Results of the National Bowel Cancer Screening Program in Qatar |
title_sort | high adenoma detection rates in fecal immunochemical test-based colorectal cancer screening: interim results of the national bowel cancer screening program in qatar |
topic | Gastroenterology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822526/ https://www.ncbi.nlm.nih.gov/pubmed/36628034 http://dx.doi.org/10.7759/cureus.32274 |
work_keys_str_mv | AT johnanilk highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT varughesebetsy highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT abushaikhashaikhas highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT hamdanahedm highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT pillaiviswapriya highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT ayashahmadm highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT vincentpaulk highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT sultankhaleel highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT alejjikhalidm highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT singhrajvir highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT alabdullasamya highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT abdulmalikmariam highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar AT alkaabisaad highadenomadetectionratesinfecalimmunochemicaltestbasedcolorectalcancerscreeninginterimresultsofthenationalbowelcancerscreeningprograminqatar |