Hcp1-loaded staphylococcal membrane vesicle vaccine protects against acute melioidosis

Burkholderia pseudomallei is the causal agent of melioidosis, a deadly tropical infectious disease that lacks a vaccine. On the basis of the attenuated Staphylococcus aureus RN4220-Δagr (RN), we engineered the RN4220-Δagr/pdhB-hcp1 strain (RN-Hcp1) to generate B. pseudomallei hemolysin-coregulated p...

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Detalles Bibliográficos
Autores principales: Zhu, Keting, Li, Gang, Li, Jia, Zheng, Mingxia, Peng, Xiaohui, Rao, Yifan, Li, Ming, Zhou, Renjie, Rao, Xiancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822774/
https://www.ncbi.nlm.nih.gov/pubmed/36618368
http://dx.doi.org/10.3389/fimmu.2022.1089225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822774/
https://www.ncbi.nlm.nih.gov/pubmed/36618368
http://dx.doi.org/10.3389/fimmu.2022.1089225

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