Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5

SARS-CoV-2 Omicron subvariants have demonstrated extensive evasion from monoclonal antibodies (mAbs) developed for clinical use, which raises an urgent need to develop new broad-spectrum mAbs. Here, we report the isolation and analysis of two anti-RBD neutralizing antibodies BA7208 and BA7125 from m...

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Detalles Bibliográficos
Autores principales: Wang, Yanqun, Yan, An, Song, Deyong, Dong, Chuangchuang, Rao, Muding, Gao, Yuanzhu, Qi, Ruxi, Ma, Xiaomin, Wang, Qiaoping, Xu, Hongguang, Liu, Hong, Han, Jing, Duan, Maoqin, Liu, Shuo, Yu, Xiaoping, Zong, Mengqi, Feng, Jianxia, Jiao, Jie, Zhang, Huimin, Li, Min, Yu, Beibei, Wang, Yanxia, Meng, Fanhao, Ni, Xiaodan, Li, Ying, Shen, Zhenduo, Sun, Baiping, Shao, Xin, Zhao, Haifeng, Zhao, Yanyan, Li, Rui, Zhang, Yanan, Du, Guangying, Lu, Jun, You, Chunna, Jiang, Hua, Zhang, Lu, Wang, Lan, Dou, Changlin, Liu, Zheng, Zhao, Jincun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822811/
https://www.ncbi.nlm.nih.gov/pubmed/36609558
http://dx.doi.org/10.1038/s41421-022-00509-9

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