Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation

Some forms of mitochondrial dysfunction induce sterile inflammation through mitochondrial DNA recognition by intracellular DNA sensors. However, the involvement of mitochondrial dynamics in mitigating such processes and their impact on muscle fitness remain unaddressed. Here we report that opposite...

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Detalles Bibliográficos
Autores principales: Irazoki, Andrea, Gordaliza-Alaguero, Isabel, Frank, Emma, Giakoumakis, Nikolaos Nikiforos, Seco, Jordi, Palacín, Manuel, Gumà, Anna, Sylow, Lykke, Sebastián, David, Zorzano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822926/
https://www.ncbi.nlm.nih.gov/pubmed/36609505
http://dx.doi.org/10.1038/s41467-022-35732-1

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