A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer

Immune checkpoint therapy in breast cancer remains restricted to triple negative patients, and long-term clinical benefit is rare. The primary aim of immune checkpoint blockade is to prevent or reverse exhausted T cell states, but T cell exhaustion in breast tumors is not well understood. Here, we u...

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Detalles Bibliográficos
Autores principales: Tietscher, Sandra, Wagner, Johanna, Anzeneder, Tobias, Langwieder, Claus, Rees, Martin, Sobottka, Bettina, de Souza, Natalie, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9822999/
https://www.ncbi.nlm.nih.gov/pubmed/36609566
http://dx.doi.org/10.1038/s41467-022-35238-w

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