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Brucella effectors NyxA and NyxB target SENP3 to modulate the subcellular localisation of nucleolar proteins

The cell nucleus is a primary target for intracellular bacterial pathogens to counteract immune responses and hijack host signalling pathways to cause disease. Here we identify two Brucella abortus effectors, NyxA and NyxB, that interfere with host protease SENP3, and this facilitates intracellular...

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Detalles Bibliográficos
Autores principales: Louche, Arthur, Blanco, Amandine, Lacerda, Thais Lourdes Santos, Cancade-Veyre, Lison, Lionnet, Claire, Bergé, Célia, Rolando, Monica, Lembo, Frédérique, Borg, Jean-Paul, Buchrieser, Carmen, Nagahama, Masami, Gérard, Francine C. A., Gorvel, Jean-Pierre, Gueguen-Chaignon, Virginie, Terradot, Laurent, Salcedo, Suzana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823007/
https://www.ncbi.nlm.nih.gov/pubmed/36609656
http://dx.doi.org/10.1038/s41467-022-35763-8