Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord

Sleep deprivation, a common perioperative period health problem, causes ocular discomfort and affects postsurgical pain. However, the mechanism of sleep deprivation-induced increased pain sensitivity is elusive. This study aims to explore the role of ROS in sleep deprivation (SD)-induced hyperalgesi...

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Detalles Bibliográficos
Autores principales: Huang, Yulin, Hao, Jing, Yang, Xuli, Xu, Li, Liu, Yue, Sun, Yu’e, Gu, Xiaoping, Zhang, Wei, Ma, Zhengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823061/
https://www.ncbi.nlm.nih.gov/pubmed/36104611
http://dx.doi.org/10.1007/s11064-022-03751-5

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