Using Genomic Structural Equation Modeling to Partition the Genetic Covariance Between Birthweight and Cardiometabolic Risk Factors into Maternal and Offspring Components in the Norwegian HUNT Study

The Barker Hypothesis posits that adverse intrauterine environments result in fetal growth restriction and increased risk of cardiometabolic disease through developmental compensations. Here we introduce a new statistical model using the genomic SEM software that is capable of simultaneously partiti...

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Detalles Bibliográficos
Autores principales: Moen, Gunn-Helen, Nivard, Michel, Bhatta, Laxmi, Warrington, Nicole M, Willer, Cristen, Åsvold, Bjørn Olav, Brumpton, Ben, Evans, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823066/
https://www.ncbi.nlm.nih.gov/pubmed/36322199
http://dx.doi.org/10.1007/s10519-022-10116-9

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