Cargando…

Ubiquilin-2 regulates pathological alpha-synuclein

The key protein implicated in Parkinson’s disease and other synucleinopathies is α-synuclein, and a post-translationally modified form of the protein, phosphorylated at serine 129 (pS129), is a principal component in Lewy bodies, a pathological hallmark of PD. While altered proteostasis has been imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Sandoval-Pistorius, Stephanie S., Gerson, Julia E., Liggans, Nyjerus, Ryou, Jaimie H., Oak, Kulin, Li, Xingli, Negron-Rios, Keyshla Y., Fischer, Svetlana, Barsh, Henry, Crowley, Emily V., Skinner, Mary E., Sharkey, Lisa M., Barmada, Sami J., Paulson, Henry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823102/
https://www.ncbi.nlm.nih.gov/pubmed/36609661
http://dx.doi.org/10.1038/s41598-022-26899-0