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Histone deacetylases inhibitor chidamide synergizes with humanized PD1 antibody to enhance T-cell chemokine expression and augment Ifn-γ response in NK-T cell lymphoma
BACKGROUND: Whether immunotherapy combined with different histone deacetylases (HDAC) inhibitors in refractory or relapsed natural killer/T-cell lymphoma (NKTCL) is superior to each agent is still lacking in head-to-head clinical trials or preclinical evidence. METHODS: NKTCL cell line xenograft mod...
Autores principales: | Wen, Tingyu, Sun, Guangyi, Jiang, Wenxin, He, Xiaohui, Shi, Yuankai, Ma, Fei, Liu, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823149/ https://www.ncbi.nlm.nih.gov/pubmed/36592514 http://dx.doi.org/10.1016/j.ebiom.2022.104420 |
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