MKL1 fuels ROS-induced proliferation of vascular smooth muscle cells by modulating FOXM1 transcription

Reactive oxygen species (ROS) promotes vascular injury and neointima formation in part by stimulating proliferation of vascular smooth muscle cells (VSMC). The underlying transcriptional mechanism, however, is not completely understood. Here we report that VSMC-specific deletion of MKL1 in mice supp...

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Detalles Bibliográficos
Autores principales: Wu, Teng, Li, Nan, Zhang, Qiumei, Liu, Ruiqi, Zhao, Hongwei, Fan, Zhiwen, Zhuo, Lili, Yang, Yuyu, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823229/
https://www.ncbi.nlm.nih.gov/pubmed/36587486
http://dx.doi.org/10.1016/j.redox.2022.102586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823229/
https://www.ncbi.nlm.nih.gov/pubmed/36587486
http://dx.doi.org/10.1016/j.redox.2022.102586

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