Cargando…

Low-Dose Administration of Cannabigerol Attenuates Inflammation and Fibrosis Associated with Methionine/Choline Deficient Diet-Induced NASH Model via Modulation of Cannabinoid Receptor

Non-Alcoholic Steatohepatitis (NASH) is the progressive form of Non-Alcoholic Fatty Liver Disease (NAFLD). NASH is distinguished by severe hepatic fibrosis and inflammation. The plant-derived, non-psychotropic compound cannabigerol (CBG) has potential anti-inflammatory effects similar to other canna...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aljobaily, Nouf, Krutsinger, Kelsey, Viereckl, Michael J., Joly, Raznin, Menlove, Bridger, Cone, Brexton, Suppes, Ailaina, Han, Yuyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823433/ https://www.ncbi.nlm.nih.gov/pubmed/36615835 http://dx.doi.org/10.3390/nu15010178

Ejemplares similares

Cannabidiol and Cannabigerol Inhibit Cholangiocarcinoma Growth In Vitro via Divergent Cell Death Pathways
por: Viereckl, Michael J., et al.
Publicado: (2022)

Biosynthesis of cannabigerol and cannabigerolic acid: the gateways to further cannabinoid production
por: Kearsey, Lewis J, et al.
Publicado: (2023)

Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence
por: Aljobaily, Nouf, et al.
Publicado: (2020)

Role of adipose tissue in methionine–choline-deficient model of non-alcoholic steatohepatitis (NASH)()
por: Jha, Pooja, et al.
Publicado: (2014)

In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid
por: Gugliandolo, Agnese, et al.
Publicado: (2018)

Honokiol affects the composition of gut microbiota and the metabolism of lipid and bile acid in methionine-choline deficiency diet-induced NASH mice
por: Zhai, Ting, et al.
Publicado: (2023)

Could the Combination of Two Non-Psychotropic Cannabinoids Counteract Neuroinflammation? Effectiveness of Cannabidiol Associated with Cannabigerol
por: Mammana, Santa, et al.
Publicado: (2019)

Acute Cannabigerol Administration Lowers Blood Pressure in Mice
por: Vernail, Victoria L., et al.
Publicado: (2022)

The Origin and Biomedical Relevance of Cannabigerol
por: Jastrząb, Anna, et al.
Publicado: (2022)

Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes
por: Navarro, Gemma, et al.
Publicado: (2018)

Appearance of choline metabolites in plasma and milk when choline is infused into the abomasum with or without methionine
por: Jenkins, C.J.R., et al.
Publicado: (2023)

Differential effects of PGAM5 knockout on high fat high fructose diet and methionine choline-deficient diet induced non-alcoholic steatohepatitis (NASH) in mice
por: Li, Li, et al.
Publicado: (2023)

The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism
por: Harada, Sayaka, et al.
Publicado: (2023)

Anti-Biofilm Activity of Cannabigerol against Streptococcus mutans
por: Aqawi, Muna, et al.
Publicado: (2021)

Anti-Bacterial Properties of Cannabigerol Toward Streptococcus mutans
por: Aqawi, Muna, et al.
Publicado: (2021)

Glucose metabolism is differentially altered by choline and methionine in bovine neonatal hepatocytes
por: Chandler, Tawny L., et al.
Publicado: (2019)

Cannabigerol Prevents Quorum Sensing and Biofilm Formation of Vibrio harveyi
por: Aqawi, Muna, et al.
Publicado: (2020)

Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives
por: Calapai, Fabrizio, et al.
Publicado: (2022)

Chronic Cannabigerol as an Effective Therapeutic for Cisplatin-Induced Neuropathic Pain
por: Nachnani, Rahul, et al.
Publicado: (2023)

THE RELATIVE EFFECTS OF PROTEIN, CHOLINE, AND METHIONINE IN THE TREATMENT OF EXPERIMENTAL DIETARY CIRRHOSIS IN THE RAT
por: Plough, Irvin C., et al.
Publicado: (1952)

Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes
por: Chandler, Tawny L., et al.
Publicado: (2017)

Effects of Dietary Methionine Levels on Choline Requirements of Starter White Pekin Ducks
por: Wen, Z. G., et al.
Publicado: (2016)

Palmitate and pyruvate carbon flux in response to choline and methionine in bovine neonatal hepatocytes
por: Chandler, T. L., et al.
Publicado: (2020)

Partial Replacement of Dietary Methionine with Betaine and Choline in Heat-Stressed Broiler Chickens
por: Mahmoudi, Mohammad, et al.
Publicado: (2018)

In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties
por: Perez, Eduardo, et al.
Publicado: (2022)

Chemotherapy‐induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol
por: Brierley, Daniel I., et al.
Publicado: (2019)

Cannabidiol and Cannabigerol Exert Antimicrobial Activity without Compromising Skin Microbiota
por: Luz-Veiga, Mariana, et al.
Publicado: (2023)

Mannich-type modifications of (−)-cannabidiol and (−)-cannabigerol leading to new, bioactive derivatives
por: Lőrincz, Eszter Boglárka, et al.
Publicado: (2023)

Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis
por: Pierce, Andrew A., et al.
Publicado: (2015)

Γ-Aminobutyric acid promotes methionine-choline deficient diet-induced nonalcoholic steatohepatitis
por: Seok Roh, Yoon, et al.
Publicado: (2017)

Osteoprotegerin deficiency aggravates methionine–choline-deficient diet-induced nonalcoholic steatohepatitis in mice
por: Wu, Shaobo, et al.
Publicado: (2023)

Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats
por: Brierley, Daniel I, et al.
Publicado: (2016)

Cannabigerol Is a Potential Therapeutic Agent in a Novel Combined Therapy for Glioblastoma
por: Lah, Tamara T., et al.
Publicado: (2021)

Cannabidiol and Cannabigerol Modify the Composition and Physicochemical Properties of Keratinocyte Membranes Exposed to UVA
por: Wroński, Adam, et al.
Publicado: (2023)

Considering choline as methionine precursor, lipoproteins transporter, hepatic promoter and antioxidant agent in dairy cows
por: Abbasi, Imtiaz Hussain Raja, et al.
Publicado: (2017)

Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood
por: Du, Juan, et al.
Publicado: (2018)

Effects of rumen-protected methionine and choline supplementation on vaginal discharge and uterine cytology of Holstein cows
por: Skenandore, Cassandra S., et al.
Publicado: (2017)

Study of Methionine Choline Deficient Diet-Induced Steatosis in Mice Using Endogenous Fluorescence Spectroscopy
por: Valor, Alma, et al.
Publicado: (2019)

Author Correction: Palmitate and pyruvate carbon flux in response to choline and methionine in bovine neonatal hepatocytes
por: Chandler, T. L., et al.
Publicado: (2021)

Effect of Phyllanthus emblica L. fruit on methionine and choline-deficiency diet-induced nonalcoholic steatohepatitis
por: Tung, Yu-Tang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_u5gehprk5j2crjd5c7s7p2i1hb