A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution

Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one pot via a tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH possess strong blue fluorescence with high quantum efficiencies over 0.70 in aqueous media. DHP-OH displays a remarkable fluorescence quenching s...

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Autores principales: Paisuwan, Waroton, Sukwattanasinitt, Mongkol, Tobisu, Mamoru, Ajavakom, Anawat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823494/
https://www.ncbi.nlm.nih.gov/pubmed/36617034
http://dx.doi.org/10.3390/s23010436
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author Paisuwan, Waroton
Sukwattanasinitt, Mongkol
Tobisu, Mamoru
Ajavakom, Anawat
author_facet Paisuwan, Waroton
Sukwattanasinitt, Mongkol
Tobisu, Mamoru
Ajavakom, Anawat
author_sort Paisuwan, Waroton
collection PubMed
description Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one pot via a tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH possess strong blue fluorescence with high quantum efficiencies over 0.70 in aqueous media. DHP-OH displays a remarkable fluorescence quenching selectively to the presence of Au3+ through the oxidation of dihydropyridine to pyridinium ion as confirmed by NMR and HRMS. DHP-OH was used to demonstrate the quantitative analysis of Au3+ in water samples with the limit of detection of 33 ppb and excellent recovery (>95%). This fluorescent probe was also applied for the determination of Au3(+) residue in the gold nanoparticle solution and a paper-based sensing strip for the on-site detection of Au3(+).
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spelling pubmed-98234942023-01-08 A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution Paisuwan, Waroton Sukwattanasinitt, Mongkol Tobisu, Mamoru Ajavakom, Anawat Sensors (Basel) Article Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one pot via a tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH possess strong blue fluorescence with high quantum efficiencies over 0.70 in aqueous media. DHP-OH displays a remarkable fluorescence quenching selectively to the presence of Au3+ through the oxidation of dihydropyridine to pyridinium ion as confirmed by NMR and HRMS. DHP-OH was used to demonstrate the quantitative analysis of Au3+ in water samples with the limit of detection of 33 ppb and excellent recovery (>95%). This fluorescent probe was also applied for the determination of Au3(+) residue in the gold nanoparticle solution and a paper-based sensing strip for the on-site detection of Au3(+). MDPI 2022-12-30 /pmc/articles/PMC9823494/ /pubmed/36617034 http://dx.doi.org/10.3390/s23010436 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Paisuwan, Waroton
Sukwattanasinitt, Mongkol
Tobisu, Mamoru
Ajavakom, Anawat
A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution
title A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution
title_full A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution
title_fullStr A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution
title_full_unstemmed A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution
title_short A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au(3+) Residue in Gold Nanoparticle Solution
title_sort dihydropyridine derivative as a highly selective fluorometric probe for quantification of au(3+) residue in gold nanoparticle solution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823494/
https://www.ncbi.nlm.nih.gov/pubmed/36617034
http://dx.doi.org/10.3390/s23010436
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