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Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy

The rapidly expanding area of regenerative medicine may soon enter a new phase owing to developments in biomaterials and their application in generating new tissues. Chemicals and synthetic drugs are currently the subject of heated debate due to their effects on human health and the environment. The...

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Detalles Bibliográficos
Autores principales: Koshy, Jijo, Sangeetha, Dhanaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823803/
https://www.ncbi.nlm.nih.gov/pubmed/36616465
http://dx.doi.org/10.3390/polym15010115
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author Koshy, Jijo
Sangeetha, Dhanaraj
author_facet Koshy, Jijo
Sangeetha, Dhanaraj
author_sort Koshy, Jijo
collection PubMed
description The rapidly expanding area of regenerative medicine may soon enter a new phase owing to developments in biomaterials and their application in generating new tissues. Chemicals and synthetic drugs are currently the subject of heated debate due to their effects on human health and the environment. Therefore, scientists seek out new products and procedures that are harmless to both the environment and human health concerns. Bio-based materials provide excellent functional qualities with a variety of applications. This study resulted in the development of a film with antimicrobial, hydrophilic, and anti-cancer properties, which is most beneficial in the medical sectors. In this study, we developed a blended biodegradable film containing agar and pectin (AP), with excellent surface functional properties framed through a casting technique. Additionally, the property can be changed by the addition of extract of hemigraphis alternata (HA) extract. The incorporation of extract in AP (APH) can be used for anti-cancer wound care therapy. The fabricated film is biodegradable, biocompatible, and non-toxic. This material is entirely based on a green methodology, and it was prepared in a concise manner without the use of any hazardous solvents. Based on the overall nature of biopolymer, the prepared material is a promising alternative to our society.
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spelling pubmed-98238032023-01-08 Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy Koshy, Jijo Sangeetha, Dhanaraj Polymers (Basel) Article The rapidly expanding area of regenerative medicine may soon enter a new phase owing to developments in biomaterials and their application in generating new tissues. Chemicals and synthetic drugs are currently the subject of heated debate due to their effects on human health and the environment. Therefore, scientists seek out new products and procedures that are harmless to both the environment and human health concerns. Bio-based materials provide excellent functional qualities with a variety of applications. This study resulted in the development of a film with antimicrobial, hydrophilic, and anti-cancer properties, which is most beneficial in the medical sectors. In this study, we developed a blended biodegradable film containing agar and pectin (AP), with excellent surface functional properties framed through a casting technique. Additionally, the property can be changed by the addition of extract of hemigraphis alternata (HA) extract. The incorporation of extract in AP (APH) can be used for anti-cancer wound care therapy. The fabricated film is biodegradable, biocompatible, and non-toxic. This material is entirely based on a green methodology, and it was prepared in a concise manner without the use of any hazardous solvents. Based on the overall nature of biopolymer, the prepared material is a promising alternative to our society. MDPI 2022-12-27 /pmc/articles/PMC9823803/ /pubmed/36616465 http://dx.doi.org/10.3390/polym15010115 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Koshy, Jijo
Sangeetha, Dhanaraj
Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy
title Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy
title_full Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy
title_fullStr Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy
title_full_unstemmed Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy
title_short Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy
title_sort hemigraphis alternata leaf extract incorporated agar/pectin-based bio-engineered wound dressing materials for effective skin cancer wound care therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823803/
https://www.ncbi.nlm.nih.gov/pubmed/36616465
http://dx.doi.org/10.3390/polym15010115
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