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Defective DNA polymerase beta invoke a cytosolic DNA mediated inflammatory response

Base excision repair (BER) has evolved to maintain the genomic integrity of DNA following endogenous and exogenous agent induced DNA base damage. In contrast, aberrant BER induces genomic instability, promotes malignant transformation and can even trigger cancer development. Previously, we have show...

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Detalles Bibliográficos
Autores principales:	Zhao, Shengyuan, Goewey Ruiz, Julia A., Sebastian, Manu, Kidane, Dawit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823925/ https://www.ncbi.nlm.nih.gov/pubmed/36624848 http://dx.doi.org/10.3389/fimmu.2022.1039009

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