Exploration of Flavonoids as Lead Compounds against Ewing Sarcoma through Molecular Docking, Pharmacogenomics Analysis, and Molecular Dynamics Simulations

Ewing sarcoma (ES) is a highly malignant carcinoma prevalent in children and most frequent in the second decade of life. It mostly occurs due to t(11;22) (q24;q12) translocation. This translocation encodes the oncogenic fusion protein EWS/FLI (Friend leukemia integration 1 transcription factor), whi...

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Detalles Bibliográficos
Autores principales: Yasir, Muhammad, Park, Jinyoung, Han, Eun-Taek, Park, Won Sun, Han, Jin-Hee, Kwon, Yong-Soo, Lee, Hee-Jae, Hassan, Mubashir, Kloczkowski, Andrzej, Chun, Wanjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823950/
https://www.ncbi.nlm.nih.gov/pubmed/36615603
http://dx.doi.org/10.3390/molecules28010414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823950/
https://www.ncbi.nlm.nih.gov/pubmed/36615603
http://dx.doi.org/10.3390/molecules28010414

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