Cargando…

Lipase-Responsive Amphotericin B Loaded PCL Nanoparticles for Antifungal Therapies

Amphotericin B is an antifungal drug used for the treatment of invasive fungal infections. However, its clinical use is limited due to its serious side effects, such as renal and cardiovascular toxicity. Furthermore, amphotericin B is administered in high doses due to its poor water solubility. Henc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uroro, Evelyn Osehontue, Bright, Richard, Hayles, Andrew, Vasilev, Krasimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823996/ https://www.ncbi.nlm.nih.gov/pubmed/36616065 http://dx.doi.org/10.3390/nano13010155

Ejemplares similares

Enhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo
por: Tang, Xiaolong, et al.
Publicado: (2014)

Antifungal efficacy of itraconazole-loaded TPGS-b-(PCL-ran-PGA) nanoparticles
por: Qiu, Lixin, et al.
Publicado: (2015)

Preparation and antifungal activity of spray-dried amphotericin B-loaded nanospheres
por: Gharib, A, et al.
Publicado: (2011)

Lipid Systems for the Delivery of Amphotericin B in Antifungal Therapy
por: Faustino, Célia, et al.
Publicado: (2020)

Design of amphotericin B oral formulation for antifungal therapy
por: Liu, Min, et al.
Publicado: (2017)

Phospholipid-Conjugated PEG-b-PCL Copolymers as Precursors of Micellar Vehicles for Amphotericin B
por: Arias, Elsa R., et al.
Publicado: (2021)

Protective and antifungal properties of Nanodisk-Amphotericin B over commercially available Amphotericin B()
por: Cho, Do-Yeon, et al.
Publicado: (2017)

Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats
por: Radwan, Mahasen A., et al.
Publicado: (2017)

Fingolimod Potentiates the Antifungal Activity of Amphotericin B
por: Wei, Lu-Qi, et al.
Publicado: (2021)

Preparation, characterization, and evaluation of amphotericin B-loaded MPEG-PCL-g-PEI micelles for local treatment of oral Candida albicans
por: Zhou, Li, et al.
Publicado: (2017)

Antileishmanial Activity of Amphotericin B-loaded-PLGA Nanoparticles: An Overview
por: Palma, Ernesto, et al.
Publicado: (2018)

Amphotericin B Loaded Polymeric Nanoparticles for Treatment of Leishmania Infections
por: Saqib, Mudassara, et al.
Publicado: (2020)

Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer
por: Tang, Xiaolong, et al.
Publicado: (2015)

Nasal Gel Loaded with Amphotericin Nanotransferosomes as Antifungal Treatment for Fungal Sinusitis
por: Hosny, Khaled M., et al.
Publicado: (2020)

Antifungal Efficacy of Amphotericin B in Candida Albicans Endocarditis Therapy: Systematic Review
por: Bezerra, Lucas Soares, et al.
Publicado: (2020)

Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
por: Feng, Runliang, et al.
Publicado: (2012)

Characterization of a Polyethylene Glycol-Amphotericin B Conjugate Loaded with Free AMB for Improved Antifungal Efficacy
por: Tan, Tessa Rui Min, et al.
Publicado: (2016)

Amphotericin B-PEG Conjugates of ZnO Nanoparticles: Enhancement Antifungal Activity with Minimal Toxicity
por: Alshahrani, Saad M., et al.
Publicado: (2022)

Inhibition of Nucleotide Biosynthesis Potentiates the Antifungal Activity of Amphotericin B
por: Banerjee, Dithi, et al.
Publicado: (2014)

Vancomycin tolerance of adherent Staphylococcus aureus is impeded by nanospike-induced physiological changes
por: Hayles, Andrew, et al.
Publicado: (2023)

Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome(®) or Fungizone™
por: Italia, Jagdishbhai L., et al.
Publicado: (2011)

Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis
por: Riezk, Alaa, et al.
Publicado: (2020)

A rapid and simple preparation of amphotericin B-loaded bacterial magnetite nanoparticles
por: Correa, Tarcisio, et al.
Publicado: (2021)

Bio-Inspired Nanostructured Ti-6Al-4V Alloy: The Role of Two Alkaline Etchants and the Hydrothermal Processing Duration on Antibacterial Activity
por: Bright, Richard, et al.
Publicado: (2022)

Antifungal Activity of Amphotericin B Conjugated to Nanosized Magnetite in the Treatment of Paracoccidioidomycosis
por: Saldanha, Camila Arruda, et al.
Publicado: (2016)

Core-in-cage structure regulated properties of ultra-small gold nanoparticles
por: Goswami, Nirmal, et al.
Publicado: (2019)

S3.4b Lactoferrin, a natural source of peptides that potentiate the antifungal activity of amphotericin B
por: Fernandes, Kenya, et al.
Publicado: (2022)

Intravenous Itraconazole vs. Amphotericin B Deoxycholate for Empirical Antifungal Therapy in Patients with Persistent Neutropenic Fever
por: Park, Sun Hee, et al.
Publicado: (2006)

Outpatient parenteral antifungal therapy (OPAT) for invasive fungal infections with intermittent dosing of liposomal amphotericin B
por: van de Peppel, Robert J, et al.
Publicado: (2020)

Intravenous itraconazole compared with liposomal amphotericin B as empirical antifungal therapy in patients with neutropaenia and persistent fever
por: Yoshida, Isao, et al.
Publicado: (2020)

Preclinical Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antifungal Activity of Liposomal Amphotericin B
por: Adler-Moore, Jill, et al.
Publicado: (2019)

Preparation of Poloxamer188-b-PCL and Study on in vitro Radioprotection Activity of Curcumin-Loaded Nanoparticles
por: Lin, Xiaona, et al.
Publicado: (2020)

Antifungal susceptibility of Candida species to copper oxide nanoparticles on polycaprolactone fibers (PCL-CuONPs)
por: Muñoz-Escobar, Antonio, et al.
Publicado: (2020)

Comparison of Antifungal Properties of Gold, Silver, and Selenium Nanoparticles Against Amphotericin B-Resistant Candida glabrata Clinical Isolates
por: Lotfali, Ensieh, et al.
Publicado: (2021)

The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry
por: Delhom, Robin, et al.
Publicado: (2020)

Eradication of Mature Bacterial Biofilms with Concurrent Improvement in Chronic Wound Healing Using Silver Nanoparticle Hydrogel Treatment
por: Haidari, Hanif, et al.
Publicado: (2021)

In vitro antifungal susceptibilities of Candida species to liposomal amphotericin B, determined using CLSI broth microdilution, and amphotericin B deoxycholate, measured using the Etest
por: Lovero, Grazia, et al.
Publicado: (2017)

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug
por: Mesa-Arango, Ana C., et al.
Publicado: (2012)

Permeability Characteristics of a New Antifungal Topical Amphotericin B Formulation with γ-Cyclodextrins
por: López-Castillo, Carmen, et al.
Publicado: (2018)

Influence of ascorbic acid and α-tocopherol on the autoxidation and in vitro antifungal activity of amphotericin B
por: Belhachemi, Mohammed Habib, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_npfrrepoisl5lcgll6ah03h3tm