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Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index
We aimed to test the hypothesis that adherence to a healthful plant-based diet (hPDI) is associated with a subsequent decrease in the incidence of asthma symptoms, with an opposite association with adherence to an unhealthful plant-based diet (uPDI). In addition, we evaluated a potential mediating r...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824479/ https://www.ncbi.nlm.nih.gov/pubmed/36615710 http://dx.doi.org/10.3390/nu15010052 |
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author | Ait-hadad, Wassila Bédard, Annabelle Delvert, Rosalie Orsi, Laurent Chanoine, Sébastien Dumas, Orianne Laouali, Nasser Le Moual, Nicole Leynaert, Bénédicte Siroux, Valérie Boutron-Ruault, Marie-Christine Varraso, Raphaëlle |
author_facet | Ait-hadad, Wassila Bédard, Annabelle Delvert, Rosalie Orsi, Laurent Chanoine, Sébastien Dumas, Orianne Laouali, Nasser Le Moual, Nicole Leynaert, Bénédicte Siroux, Valérie Boutron-Ruault, Marie-Christine Varraso, Raphaëlle |
author_sort | Ait-hadad, Wassila |
collection | PubMed |
description | We aimed to test the hypothesis that adherence to a healthful plant-based diet (hPDI) is associated with a subsequent decrease in the incidence of asthma symptoms, with an opposite association with adherence to an unhealthful plant-based diet (uPDI). In addition, we evaluated a potential mediating role of body mass index (BMI) and the modifying effect of smoking. Among 5700 elderly women from the French Asthma-E3N study with dietary data in 1993 and 2005, we assessed the incidence of asthma symptoms in 2018 among women with no asthma symptoms in 2011. BMI was evaluated in 2008. Mediation analyses in the counterfactual framework were used to disentangle total, direct, and indirect effects mediated by BMI. We found that both healthful and unhealthful plant-based diets were associated with a lower incidence of asthma symptoms over time, mediated by BMI (OR (95%CI) for the indirect effect: 0.94 (0.89–1.00) for hPDI and 0.92 (0.70–1.00) for uPDI)). Associations with both healthful and unhealthful PDIs were mediated by changes in BMI by 33% and 89%, respectively. Plant-based diets (healthful and unhealthful) were associated with subsequently reduced incidences of asthma symptoms over time, partly or almost totally mediated by BMI according to their nutritional quality. |
format | Online Article Text |
id | pubmed-9824479 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98244792023-01-08 Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index Ait-hadad, Wassila Bédard, Annabelle Delvert, Rosalie Orsi, Laurent Chanoine, Sébastien Dumas, Orianne Laouali, Nasser Le Moual, Nicole Leynaert, Bénédicte Siroux, Valérie Boutron-Ruault, Marie-Christine Varraso, Raphaëlle Nutrients Article We aimed to test the hypothesis that adherence to a healthful plant-based diet (hPDI) is associated with a subsequent decrease in the incidence of asthma symptoms, with an opposite association with adherence to an unhealthful plant-based diet (uPDI). In addition, we evaluated a potential mediating role of body mass index (BMI) and the modifying effect of smoking. Among 5700 elderly women from the French Asthma-E3N study with dietary data in 1993 and 2005, we assessed the incidence of asthma symptoms in 2018 among women with no asthma symptoms in 2011. BMI was evaluated in 2008. Mediation analyses in the counterfactual framework were used to disentangle total, direct, and indirect effects mediated by BMI. We found that both healthful and unhealthful plant-based diets were associated with a lower incidence of asthma symptoms over time, mediated by BMI (OR (95%CI) for the indirect effect: 0.94 (0.89–1.00) for hPDI and 0.92 (0.70–1.00) for uPDI)). Associations with both healthful and unhealthful PDIs were mediated by changes in BMI by 33% and 89%, respectively. Plant-based diets (healthful and unhealthful) were associated with subsequently reduced incidences of asthma symptoms over time, partly or almost totally mediated by BMI according to their nutritional quality. MDPI 2022-12-22 /pmc/articles/PMC9824479/ /pubmed/36615710 http://dx.doi.org/10.3390/nu15010052 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ait-hadad, Wassila Bédard, Annabelle Delvert, Rosalie Orsi, Laurent Chanoine, Sébastien Dumas, Orianne Laouali, Nasser Le Moual, Nicole Leynaert, Bénédicte Siroux, Valérie Boutron-Ruault, Marie-Christine Varraso, Raphaëlle Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index |
title | Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index |
title_full | Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index |
title_fullStr | Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index |
title_full_unstemmed | Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index |
title_short | Plant-Based Diets and the Incidence of Asthma Symptoms among Elderly Women, and the Mediating Role of Body Mass Index |
title_sort | plant-based diets and the incidence of asthma symptoms among elderly women, and the mediating role of body mass index |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824479/ https://www.ncbi.nlm.nih.gov/pubmed/36615710 http://dx.doi.org/10.3390/nu15010052 |
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