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Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing
One way of optically monitoring molecule concentrations is to utilise the high sensitivity of the transmission and reflection rates of Fabry-Pérot cavities to changes of their optical properties. Up to now, intrinsic and extrinsic Fabry-Pérot cavity sensors have been considered with analytes either...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824650/ https://www.ncbi.nlm.nih.gov/pubmed/36616984 http://dx.doi.org/10.3390/s23010385 |
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author | Al Ghamdi, Abeer Dawson, Benjamin Jose, Gin Beige, Almut |
author_facet | Al Ghamdi, Abeer Dawson, Benjamin Jose, Gin Beige, Almut |
author_sort | Al Ghamdi, Abeer |
collection | PubMed |
description | One way of optically monitoring molecule concentrations is to utilise the high sensitivity of the transmission and reflection rates of Fabry-Pérot cavities to changes of their optical properties. Up to now, intrinsic and extrinsic Fabry-Pérot cavity sensors have been considered with analytes either being placed inside the resonator or coupled to evanescent fields on the outside. Here we demonstrate that Fabry-Pérot cavities can also be used to monitor molecule concentrations non-invasively and remotely, since the reflection of light from the target molecules back into the Fabry-Pérot cavity adds upwards peaks to the minima of its overall reflection rate. Detecting the amplitude of these peaks reveals information about molecule concentrations. By using an array of optical cavities, a wide range of frequencies can be probed at once and a unique optical fingerprint can be obtained. |
format | Online Article Text |
id | pubmed-9824650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98246502023-01-08 Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing Al Ghamdi, Abeer Dawson, Benjamin Jose, Gin Beige, Almut Sensors (Basel) Article One way of optically monitoring molecule concentrations is to utilise the high sensitivity of the transmission and reflection rates of Fabry-Pérot cavities to changes of their optical properties. Up to now, intrinsic and extrinsic Fabry-Pérot cavity sensors have been considered with analytes either being placed inside the resonator or coupled to evanescent fields on the outside. Here we demonstrate that Fabry-Pérot cavities can also be used to monitor molecule concentrations non-invasively and remotely, since the reflection of light from the target molecules back into the Fabry-Pérot cavity adds upwards peaks to the minima of its overall reflection rate. Detecting the amplitude of these peaks reveals information about molecule concentrations. By using an array of optical cavities, a wide range of frequencies can be probed at once and a unique optical fingerprint can be obtained. MDPI 2022-12-29 /pmc/articles/PMC9824650/ /pubmed/36616984 http://dx.doi.org/10.3390/s23010385 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Al Ghamdi, Abeer Dawson, Benjamin Jose, Gin Beige, Almut Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing |
title | Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing |
title_full | Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing |
title_fullStr | Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing |
title_full_unstemmed | Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing |
title_short | Remote Non-Invasive Fabry-Pérot Cavity Spectroscopy for Label-Free Sensing |
title_sort | remote non-invasive fabry-pérot cavity spectroscopy for label-free sensing |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824650/ https://www.ncbi.nlm.nih.gov/pubmed/36616984 http://dx.doi.org/10.3390/s23010385 |
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