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Glucagon-like Peptide 1 Receptor Activation Inhibits Microglial Pyroptosis via Promoting Mitophagy to Alleviate Depression-like Behaviors in Diabetic Mice
Depression is a frequent and serious comorbidity associated with diabetes which adversely affects prognosis and quality of life. Glucagon-like peptide-1 receptor (GLP-1R) agonists, widely used in the treatment of diabetes, are reported to exert neuroprotective effects in the central nervous system....
Autores principales: | Yang, Fan, Wang, Xinshang, Qi, Jingyu, Zhang, Kun, Jiang, Yongli, Feng, Ban, Lv, Tao, Yang, Le, Yang, Qi, Zhao, Minggao, Liu, Shuibing, Ma, Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824834/ https://www.ncbi.nlm.nih.gov/pubmed/36615696 http://dx.doi.org/10.3390/nu15010038 |
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