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Differential CpG DNA methylation of peripheral B cells, CD4(+) T cells, and salivary gland tissues in IgG4-related disease

OBJECTIVES: Immunoglobulin-G4-related disease (IgG4-RD) is a distinct systemic autoimmune-mediated disease manifesting as chronic inflammation and tissue fibrosis. Since the role of DNA methylation in the pathogenesis of IgG4-RD is still unclear, we conduct this study to investigate epigenetic modif...

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Detalles Bibliográficos
Autores principales: Wu, Xunyao, Wang, Anqi, Wang, Mu, Peng, Yu, Chen, Yingying, Li, Jieqiong, Liu, Zheng, Lu, Hui, Zhou, Jiaxin, Peng, Linyi, Zhao, Yan, Zeng, Xiaofeng, Fei, Yunyun, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824958/
https://www.ncbi.nlm.nih.gov/pubmed/36609529
http://dx.doi.org/10.1186/s13075-022-02978-5