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ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner

BACKGROUND: N6-methyladenosine (m6A) is a prevalent modification of mRNA and is known to play important roles in tumorigenesis in many types of cancer. The function of N6-methyladenosine (m6A) RNA methylation depends on a variety of methyltransferases and demethylases. AlkB homolog 5 (ALKBH5) is a d...

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Detalles Bibliográficos
Autores principales: Wang, Weijian, Huang, Qibo, Liao, Zhibin, Zhang, Hongwei, Liu, Yachong, Liu, Furong, Chen, Xiaoping, Zhang, Bixiang, Chen, Yan, Zhu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825045/
https://www.ncbi.nlm.nih.gov/pubmed/36609413
http://dx.doi.org/10.1186/s40164-022-00370-2

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