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Rational design of hybrid DNA–RNA triplex structures as modulators of transcriptional activity in vitro

Triplex nanostructures can be formed in vitro in the promoter region of DNA templates, and it is commonly accepted that these assemblies inhibit the transcription of the downstream genes. Herein, a proof of concept highlighting the possibility of the up- or downregulation of RNA transcription is pre...

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Detalles Bibliográficos
Autores principales:	Cecconello, Alessandro, Magro, Massimiliano, Vianello, Fabio, Simmel, Friedrich C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825147/ https://www.ncbi.nlm.nih.gov/pubmed/36537227 http://dx.doi.org/10.1093/nar/gkac1131

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