The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3

The Notch pathway transmits signals between neighboring cells to elicit downstream transcriptional programs. Notch is a major regulator of cell fate specification, proliferation, and apoptosis, such that aberrant signaling leads to a pleiotropy of human diseases, including developmental disorders an...

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Detalles Bibliográficos
Autores principales: Hall, Daniel, Giaimo, Benedetto Daniele, Park, Sung-Soo, Hemmer, Wiebke, Friedrich, Tobias, Ferrante, Francesca, Bartkuhn, Marek, Yuan, Zhenyu, Oswald, Franz, Borggrefe, Tilman, Rual, Jean-François, Kovall, Rhett A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825171/
https://www.ncbi.nlm.nih.gov/pubmed/36477367
http://dx.doi.org/10.1093/nar/gkac1137

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