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RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation

Mitochondrial RNA metabolism is suggested to occur in identified compartmentalized foci, i.e. mitochondrial RNA granules (MRGs). Mitochondrial aminoacyl-tRNA synthetases (mito aaRSs) catalyze tRNA charging and are key components in mitochondrial gene expression. Mutations of mito aaRSs are associate...

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Detalles Bibliográficos
Autores principales:	Peng, Gui-Xin, Mao, Xue-Ling, Cao, Yating, Yao, Shi-Ying, Li, Qing-Run, Chen, Xin, Wang, En-Duo, Zhou, Xiao-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825176/ https://www.ncbi.nlm.nih.gov/pubmed/36503967 http://dx.doi.org/10.1093/nar/gkac1141

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