Cargando…

Quercetin Inhibits Pyroptosis in Diabetic Cardiomyopathy through the Nrf2 Pathway

The present study investigated whether quercetin promotes the nuclear translocation of nuclear factor erythroid-2-related factor 2 (Nrf2) to inhibit pyroptosis progression and ameliorate diabetic cardiomyopathy. We evaluated the protective effects of quercetin against diabetic cardiomyopathy by anal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Zhang, Jing, Zhou, Pinfang, Kang, Chao, Shi, Shaohuan, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825227/ https://www.ncbi.nlm.nih.gov/pubmed/36624860 http://dx.doi.org/10.1155/2022/9723632

Ejemplares similares

Curcumin Improves Diabetic Cardiomyopathy by Inhibiting Pyroptosis through AKT/Nrf2/ARE Pathway
por: Wei, Zhang, et al.
Publicado: (2023)

Curcumin Attenuates Ferroptosis-Induced Myocardial Injury in Diabetic Cardiomyopathy through the Nrf2 Pathway
por: Wei, Zhang, et al.
Publicado: (2022)

Resveratrol inhibits ferroptosis and decelerates heart failure progression via Sirt1/p53 pathway activation
por: Zhang, Wei, et al.
Publicado: (2023)

Dexmedetomidine ameliorates diabetic cardiomyopathy by inhibiting ferroptosis through the Nrf2/GPX4 pathway
por: Li, Fan, et al.
Publicado: (2023)

Pyroptosis and Its Regulation in Diabetic Cardiomyopathy
por: Lu, Yafang, et al.
Publicado: (2022)

CD38 Deficiency Alleviates Diabetic Cardiomyopathy by Coordinately Inhibiting Pyroptosis and Apoptosis
por: Wang, Ling-Fang, et al.
Publicado: (2023)

Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo
por: Chen, Hsin-Yuan, et al.
Publicado: (2022)

Quercetin protects cadmium-induced renal injuries in mice by inhibiting cell pyroptosis
por: Wang, Juyu, et al.
Publicado: (2023)

Potential diabetic cardiomyopathy therapies targeting pyroptosis: A mini review
por: Jia, Yu, et al.
Publicado: (2022)

Pyroptosis-Related Inflammasome Pathway: A New Therapeutic Target for Diabetic Cardiomyopathy
por: Cai, Zhengyao, et al.
Publicado: (2022)

Kynurenic acid inhibits macrophage pyroptosis by suppressing ROS production via activation of the NRF2 pathway
por: Gao, Yuwei, et al.
Publicado: (2023)

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
por: Wang, Xiang, et al.
Publicado: (2022)

Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway
por: Sun, Huanhuan, et al.
Publicado: (2022)

Protocatechuic acid and quercetin attenuate ETEC-caused IPEC-1 cell inflammation and injury associated with inhibition of necroptosis and pyroptosis signaling pathways
por: Xiao, Kan, et al.
Publicado: (2023)

Pyrroloquinoline quinone ameliorates diabetic cardiomyopathy by inhibiting the pyroptosis signaling pathway in C57BL/6 mice and AC16 cells
por: Qu, Xue-feng, et al.
Publicado: (2022)

AR/PCC herb pair inhibits osteoblast pyroptosis to alleviate diabetes‐related osteoporosis by activating Nrf2/Keap1 pathway
por: Fu, Fangda, et al.
Publicado: (2023)

Expression of miRNAs in plasma exosomes derived from patients with atrial fibrillation
por: Wei, Zhang, et al.
Publicado: (2020)

Quercetin Attenuates Cardiac Hypertrophy by Inhibiting Mitochondrial Dysfunction Through SIRT3/PARP-1 Pathway
por: Chen, Wen-Jing, et al.
Publicado: (2021)

KLF9 Aggravates Streptozotocin-Induced Diabetic Cardiomyopathy by Inhibiting PPARγ/NRF2 Signalling
por: Li, Fangfang, et al.
Publicado: (2022)

Protective Effects of Quercetin on Mitochondrial Biogenesis in Experimental Traumatic Brain Injury via the Nrf2 Signaling Pathway
por: Li, Xiang, et al.
Publicado: (2016)

Quercetin ameliorates diabetic encephalopathy through SIRT1/ER stress pathway in db/db mice
por: Hu, Tian, et al.
Publicado: (2020)

Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway
por: Ding, Baozhu, et al.
Publicado: (2021)

Diabetic Cardiomyopathy and Its Prevention by Nrf2: Current Status
por: Chen, Jing, et al.
Publicado: (2014)

Quercetin Alleviates the Progression of Breast Cancer-Related Depression via Inhibiting the Pyroptosis and Promoting the Immune Response
por: Zhu, Qing, et al.
Publicado: (2022)

Quercetin is a Potential Therapy for Rheumatoid Arthritis via Targeting Caspase-8 Through Ferroptosis and Pyroptosis
por: Zheng, Qingcong, et al.
Publicado: (2023)

PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψ(m) Pathways by Inhibiting Pyroptosis
por: Feng, Zhencheng, et al.
Publicado: (2023)

CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes
por: Yuan, Qiong, et al.
Publicado: (2023)

Glutathione homeostasis is significantly altered by quercetin via the Keap1/Nrf2 and MAPK signaling pathways in rats
por: Gao, Weina, et al.
Publicado: (2018)

Quercetin Protects against Lipopolysaccharide-Induced Intestinal Oxidative Stress in Broiler Chickens through Activation of Nrf2 Pathway
por: Sun, Lei, et al.
Publicado: (2020)

Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis
por: Huang, Yongzhou, et al.
Publicado: (2023)

Corrigendum to “Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway”
por: Ding, Baozhu, et al.
Publicado: (2022)

Puerarin-V Improve Mitochondrial Respiration and Cardiac Function in a Rat Model of Diabetic Cardiomyopathy via Inhibiting Pyroptosis Pathway through P2X7 Receptors
por: Sun, Shuchan, et al.
Publicado: (2022)

Melatonin attenuates high glucose‑induced endothelial cell pyroptosis by activating the Nrf2 pathway to inhibit NLRP3 inflammasome activation
por: Wang, Xuebin, et al.
Publicado: (2023)

Mechanisms of Quercetin against atrial fibrillation explored by network pharmacology combined with molecular docking and experimental validation
por: Tan, Xin, et al.
Publicado: (2022)

Modulation of Nrf2 by quercetin in doxorubicin-treated rats
por: Sharma, Anish, et al.
Publicado: (2020)

Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro
por: Gao, Ge, et al.
Publicado: (2022)

Bakuchiol Alleviates Hyperglycemia-Induced Diabetic Cardiomyopathy by Reducing Myocardial Oxidative Stress via Activating the SIRT1/Nrf2 Signaling Pathway
por: Ma, Wenshuai, et al.
Publicado: (2020)

Exogenous spermine inhibits high glucose/oxidized LDL-induced oxidative stress and macrophage pyroptosis by activating the Nrf2 pathway
por: Qiu, Yuxuan, et al.
Publicado: (2022)

Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway
por: Huang, Cancan, et al.
Publicado: (2020)

Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling
por: Lin, Yuqing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_svdnjl6lf9hdtdoub6m9ck64bd