A Revised Perspective on the Evolution of Troponin I and Troponin T Gene Families in Vertebrates

The troponin (Tn) complex, responsible for the Ca(2+) activation of striated muscle, is composed of three interacting protein subunits: TnC, TnI, and TnT, encoded by TNNC, TNNI, and TNNT genes. TNNI and TNNT are sister gene families, and in mammals the three TNNI paralogs (TNNI1, TNNI2, TNNI3), whic...

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Detalles Bibliográficos
Autores principales: Joyce, William, Ripley, Daniel M, Gillis, Todd, Black, Amanda Coward, Shiels, Holly A, Hoffmann, Federico G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825255/
https://www.ncbi.nlm.nih.gov/pubmed/36518048
http://dx.doi.org/10.1093/gbe/evac173

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