Cargando…

Global lysine methylome profiling using systematically characterized affinity reagents

Lysine methylation modulates the function of histone and non-histone proteins, and the enzymes that add or remove lysine methylation—lysine methyltransferases (KMTs) and lysine demethylases (KDMs), respectively—are frequently mutated and dysregulated in human diseases. Identification of lysine methy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Berryhill, Christine A., Hanquier, Jocelyne N., Doud, Emma H., Cordeiro-Spinetti, Eric, Dickson, Bradley M., Rothbart, Scott B., Mosley, Amber L., Cornett, Evan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825382/ https://www.ncbi.nlm.nih.gov/pubmed/36611042 http://dx.doi.org/10.1038/s41598-022-27175-x

Ejemplares similares

Identification of nonhistone substrates of the lysine methyltransferase PRDM9
por: Hanquier, Jocelyne N., et al.
Publicado: (2023)

A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity
por: Cornett, Evan M., et al.
Publicado: (2018)

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance
por: Vaughan, Robert M, et al.
Publicado: (2018)

A physical basis for quantitative ChIP-sequencing
por: Dickson, Bradley M., et al.
Publicado: (2020)

Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
por: Alm, Tove, et al.
Publicado: (2016)

An overview of enzymatic reagents for the removal of affinity tags
por: Waugh, David S.
Publicado: (2011)

Affimer proteins are versatile and renewable affinity reagents
por: Tiede, Christian, et al.
Publicado: (2017)

Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing
por: Chen, Qiujia, et al.
Publicado: (2022)

A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation
por: Colino-Sanguino, Yolanda, et al.
Publicado: (2019)

Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step
por: Huang, Renhua, et al.
Publicado: (2015)

Branched Multimeric Peptides as Affinity Reagents for the Detection of α-Klotho Protein
por: Ye, Xiyun, et al.
Publicado: (2023)

A simple method for developing lysine targeted covalent protein reagents
por: Gabizon, Ronen, et al.
Publicado: (2023)

Translation of ceragenin affinity for bacteria to an imaging reagent for infection
por: Bandara, Nilantha, et al.
Publicado: (2019)

ELISA reagent coverage evaluation by affinity purification tandem mass spectrometry
por: Henry, Scott M., et al.
Publicado: (2017)

Reversible protein affinity-labelling using bromomaleimide-based reagents
por: Nathani, Ramiz I., et al.
Publicado: (2013)

Consequences of VHL Loss on Global DNA Methylome
por: Robinson, Claire M., et al.
Publicado: (2018)

A Comparative Study on the Effects of the Lysine Reagent Pyridoxal 5-Phosphate and Some Thiol Reagents in Opening the Tl(+)-Induced Mitochondrial Permeability Transition Pore
por: Korotkov, Sergey M., et al.
Publicado: (2023)

Rapid de novo discovery of peptidomimetic affinity reagents for human angiotensin converting enzyme 2
por: Zhang, Genwei, et al.
Publicado: (2022)

Influence of Target Concentration and Background Binding on In Vitro Selection of Affinity Reagents
por: Wang, Jinpeng, et al.
Publicado: (2012)

A Recombinant Affinity Reagent Specific for a Phosphoepitope of Akt1
por: McGinnis, Jennifer E., et al.
Publicado: (2018)

Single-Domain Antibodies As Versatile Affinity Reagents for Analytical and Diagnostic Applications
por: Gonzalez-Sapienza, Gualberto, et al.
Publicado: (2017)

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation
por: Vaughan, Robert M., et al.
Publicado: (2019)

Skeletal muscle-specific overexpression of miR-486 limits mammary tumor-induced skeletal muscle functional limitations
por: Wang, Ruizhong, et al.
Publicado: (2022)

Skeletal muscle-specific overexpression of miR-486 limits mammary tumor-induced skeletal muscle functional limitations
por: Wang, Ruizhong, et al.
Publicado: (2022)

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1
por: Vaughan, Robert M., et al.
Publicado: (2018)

Generation of Affinity Purified Antibody Reagents for Specific Determination of Efruxifermin in Biological Matrices
por: Kinne, Adam S, et al.
Publicado: (2021)

Development of an experiment-split method for benchmarking the generalization of a PTM site predictor: Lysine methylome as an example
por: Zou, Guoyang, et al.
Publicado: (2021)

Mechanisms of spinophilin-dependent pancreas dysregulation underlying diabesity
por: Stickel, Kaitlyn C., et al.
Publicado: (2023)

3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers
por: Jha, Ramesh K., et al.
Publicado: (2012)

Unraveling the Roots of Selectivity of Peptide Affinity Reagents for Structurally Similar Ribosomal Inactivating Protein Derivatives
por: Sarkes, Deborah A., et al.
Publicado: (2016)

Global effects of identity and aging on the human sperm methylome
por: de Sena Brandine, Guilherme, et al.
Publicado: (2023)

NF-κB Signaling Is Regulated by Fucosylation in Metastatic Breast Cancer Cells
por: Doud, Emma H., et al.
Publicado: (2020)

Proteome-wide quantitative analysis of redox cysteine availability in the Drosophila melanogaster eye reveals oxidation of phototransduction machinery during blue light exposure and age
por: Stanhope, Sarah C., et al.
Publicado: (2023)

Tandem phage-display for the identification of non-overlapping binding pairs of recombinant affinity reagents
por: Gorman, Kevin T., et al.
Publicado: (2017)

Engineered polymer nanoparticles incorporating l-amino acid groups as affinity reagents for fibrinogen
por: Zhu, Yongyan, et al.
Publicado: (2021)

Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1
por: Buist, Hanna K., et al.
Publicado: (2021)

Lysines Acetylome and Methylome Profiling of H3 and H4 Histones in Trichostatin A—Treated Stem Cells
por: Cozzolino, Flora, et al.
Publicado: (2021)

A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions
por: Kupai, Ariana, et al.
Publicado: (2020)

Analysis of histone antibody specificity directly in sequencing data using siQ-ChIP
por: Kupai, Ariana, et al.
Publicado: (2023)

Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0
por: Dickson, Bradley M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h7hjm3tku3ere1k37mjca49u34