Annotation and evaluation of base editing outcomes in multiple cell types using CRISPRbase

CRISPR-Cas base editing (BE) system is a powerful tool to expand the scope and efficiency of genome editing with single-nucleotide resolution. The editing efficiency, product purity, and off-target effect differ among various BE systems. Herein, we developed CRISPRbase (http://crisprbase.maolab.org)...

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Detalles Bibliográficos
Autores principales: Fan, Jibiao, Shi, Leisheng, Liu, Qi, Zhu, Zhipeng, Wang, Fan, Song, Runxian, Su, Jimeng, Zhou, Degui, Chen, Xiao, Li, Kailong, Xue, Lixiang, Sun, Lichao, Mao, Fengbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825451/
https://www.ncbi.nlm.nih.gov/pubmed/36350608
http://dx.doi.org/10.1093/nar/gkac967

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