The Cancer Epitope Database and Analysis Resource (CEDAR)

We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as the...

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Autores principales: Koşaloğlu-Yalçın, Zeynep, Blazeska, Nina, Vita, Randi, Carter, Hannah, Nielsen, Morten, Schoenberger, Stephen, Sette, Alessandro, Peters, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825495/
https://www.ncbi.nlm.nih.gov/pubmed/36250634
http://dx.doi.org/10.1093/nar/gkac902
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author Koşaloğlu-Yalçın, Zeynep
Blazeska, Nina
Vita, Randi
Carter, Hannah
Nielsen, Morten
Schoenberger, Stephen
Sette, Alessandro
Peters, Bjoern
author_facet Koşaloğlu-Yalçın, Zeynep
Blazeska, Nina
Vita, Randi
Carter, Hannah
Nielsen, Morten
Schoenberger, Stephen
Sette, Alessandro
Peters, Bjoern
author_sort Koşaloğlu-Yalçın, Zeynep
collection PubMed
description We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.
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spelling pubmed-98254952023-01-10 The Cancer Epitope Database and Analysis Resource (CEDAR) Koşaloğlu-Yalçın, Zeynep Blazeska, Nina Vita, Randi Carter, Hannah Nielsen, Morten Schoenberger, Stephen Sette, Alessandro Peters, Bjoern Nucleic Acids Res NAR Breakthrough Article We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/. Oxford University Press 2022-10-17 /pmc/articles/PMC9825495/ /pubmed/36250634 http://dx.doi.org/10.1093/nar/gkac902 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle NAR Breakthrough Article
Koşaloğlu-Yalçın, Zeynep
Blazeska, Nina
Vita, Randi
Carter, Hannah
Nielsen, Morten
Schoenberger, Stephen
Sette, Alessandro
Peters, Bjoern
The Cancer Epitope Database and Analysis Resource (CEDAR)
title The Cancer Epitope Database and Analysis Resource (CEDAR)
title_full The Cancer Epitope Database and Analysis Resource (CEDAR)
title_fullStr The Cancer Epitope Database and Analysis Resource (CEDAR)
title_full_unstemmed The Cancer Epitope Database and Analysis Resource (CEDAR)
title_short The Cancer Epitope Database and Analysis Resource (CEDAR)
title_sort cancer epitope database and analysis resource (cedar)
topic NAR Breakthrough Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825495/
https://www.ncbi.nlm.nih.gov/pubmed/36250634
http://dx.doi.org/10.1093/nar/gkac902
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