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ClusterCAD 2.0: an updated computational platform for chimeric type I polyketide synthase and nonribosomal peptide synthetase design

Megasynthase enzymes such as type I modular polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) play a central role in microbial chemical warfare because they can evolve rapidly by shuffling parts (catalytic domains) to produce novel chemicals. If we can understand the design ru...

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Detalles Bibliográficos
Autores principales:	Tao, Xavier B, LaFrance, Sarah, Xing, Yifei, Nava, Alberto A, Martin, Hector Garcia, Keasling, Jay D, Backman, Tyler W H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Database Issue
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825560/ https://www.ncbi.nlm.nih.gov/pubmed/36416273 http://dx.doi.org/10.1093/nar/gkac1075

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