Fast, accurate, and racially unbiased pan-cancer tumor-only variant calling with tabular machine learning

Accurately identifying somatic mutations is essential for precision oncology and crucial for calculating tumor-mutational burden (TMB), an important predictor of response to immunotherapy. For tumor-only variant calling (i.e., when the cancer biopsy but not the patient’s normal tissue sample is sequ...

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Detalles Bibliográficos
Autores principales: McLaughlin, R. Tyler, Asthana, Maansi, Di Meo, Marc, Ceccarelli, Michele, Jacob, Howard J., Masica, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825621/
https://www.ncbi.nlm.nih.gov/pubmed/36611079
http://dx.doi.org/10.1038/s41698-022-00340-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825621/
https://www.ncbi.nlm.nih.gov/pubmed/36611079
http://dx.doi.org/10.1038/s41698-022-00340-1

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