TCRconv: predicting recognition between T cell receptors and epitopes using contextualized motifs

MOTIVATION: T cells use T cell receptors (TCRs) to recognize small parts of antigens, called epitopes, presented by major histocompatibility complexes. Once an epitope is recognized, an immune response is initiated and T cell activation and proliferation by clonal expansion begin. Clonal populations...

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Detalles Bibliográficos
Autores principales: Jokinen, Emmi, Dumitrescu, Alexandru, Huuhtanen, Jani, Gligorijević, Vladimir, Mustjoki, Satu, Bonneau, Richard, Heinonen, Markus, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9825763/
https://www.ncbi.nlm.nih.gov/pubmed/36477794
http://dx.doi.org/10.1093/bioinformatics/btac788

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