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Site Specific Preparation of N‐Glycosylated Peptides: Thioamide‐Directed Activation of Aspartate

A site‐specific method for the preparation of N‐glycosylated peptides is described. Incorporation of a peptide backbone thioamide linkage adjacent to an Asp residue facilitates a Ag(I)‐promoted, site‐specific conversion to N‐glycosylated Asn residues in peptides.

Detalles Bibliográficos
Autores principales:	Taresh, Ameer B., Hutton, Craig A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826000/ https://www.ncbi.nlm.nih.gov/pubmed/36068172 http://dx.doi.org/10.1002/anie.202210367

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