Cargando…

Effects of a novel weight‐loss combination product containing orlistat and acarbose on obesity: A randomized, placebo‐controlled trial

OBJECTIVE: The aim of this study was to evaluate the effect of a novel, oral, modified‐release formulation of the lipase inhibitor orlistat and the glucosidase/amylase inhibitor acarbose (denoted EMP16) on relative body weight after 26 weeks compared with placebo. METHODS: The randomized, double‐bli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Holmbäck, Ulf, Grudén, Stefan, Litorp, Helena, Willhems, Daniel, Kuusk, Sandra, Alderborn, Göran, Söderhäll, Arvid, Forslund, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826204/ https://www.ncbi.nlm.nih.gov/pubmed/36123783 http://dx.doi.org/10.1002/oby.23557

Ejemplares similares

Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose
por: Grudén, Stefan, et al.
Publicado: (2021)

Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
por: Holmbäck, Ulf, et al.
Publicado: (2020)

Taking Orlistat: Predicting Weight Loss over 6 Months
por: Hollywood, Amelia, et al.
Publicado: (2011)

The effect of orlistat and weight loss diet on plasma ghrelin and obestatin
por: Pamuk, Baris, et al.
Publicado: (2018)

Comparision of Efficacy and Safety of Orlistat vs Placebo in Obese Patients in Pakistan
por: Syed, Asghar Hussain, et al.
Publicado: (2020)

Comparison of orlistat and orlistat plus metformin therapy between diabetic and nondiabetic groups
por: Gunay, Yasemin Emur, et al.
Publicado: (2023)

Impact of Orlistat-Induced Weight Loss on Diastolic Function and Heart Rate Variability in Severely Obese Subjects with Diabetes
por: Martin, Julie, et al.
Publicado: (2011)

The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort
por: Douglas, Ian J, et al.
Publicado: (2015)

Obesity management: Update on orlistat
por: Drew, Belinda S, et al.
Publicado: (2007)

On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients
por: Rudén, Jonas, et al.
Publicado: (2020)

Acarbose is again on the stage
por: Altay, Mustafa
Publicado: (2022)

MARCH: factors associated with weight loss in patients with newly diagnosed type 2 diabetes treated with acarbose or metformin
por: Wang, Na, et al.
Publicado: (2018)

Orlistat in the prevention of diabetes in the obese patient
por: Mancini, Marcio C, et al.
Publicado: (2008)

Macrocytic Anemia and Thrombocytopenia Induced by Orlistat
por: Palacios-Martinez, David, et al.
Publicado: (2013)

Acute oxalate nephropathy associated with orlistat
por: Humayun, Youshay, et al.
Publicado: (2016)

Orlistat in polycystic ovarian syndrome reduces weight with improvement in lipid profile and pregnancy rates
por: Kumar, Pratap, et al.
Publicado: (2014)

Circadian Misalignment Augments Markers of Insulin Resistance and Inflammation, Independently of Sleep Loss
por: Leproult, Rachel, et al.
Publicado: (2014)

Comparative effects of sibutramine and orlistat on weight loss, glucose metabolism and leptin levels in non-diabetic obese patients: A prospective study
por: Anagnostis, Panagiotis, et al.
Publicado: (2012)

Evaluation of efficacy and safety of orlistat in obese patients
por: Jain, Suyog S., et al.
Publicado: (2011)

The Effect of Orlistat on Sterol Metabolism in Obese Patients
por: Kwon, Yu-Jin, et al.
Publicado: (2022)

Influence of intense multidisciplinary follow-up and orlistat on weight reduction in a primary care setting
por: Feigenbaum, Amiel, et al.
Publicado: (2005)

Exploration of suitable pharmacodynamic parameters for acarbose bioequivalence evaluation: A series of clinical trials with branded acarbose
por: Huang, Jie, et al.
Publicado: (2020)

Evaluation of the Effects of Acarbose on Weight and Metabolic, Inflammatory, and Cardiovascular Markers in Patients with Obesity and Overweight
por: Khalili, Noushin, et al.
Publicado: (2020)

On the potential of acarbose to reduce cardiovascular disease
por: Standl, Eberhard, et al.
Publicado: (2014)

High Sensitivity of Giardia duodenalis to Tetrahydrolipstatin (Orlistat) In Vitro
por: Hahn, Juliane, et al.
Publicado: (2013)

Orlistat-Induced Gut Microbiota Modification in Obese Mice
por: Ke, Jing, et al.
Publicado: (2020)

Acarbose improves glycemic control and reduces body weight: Subanalysis data of South Asia region
por: Kalra, S, et al.
Publicado: (2013)

Evaluation of effect of acarbose consumption on weight losing in non-diabetic overweight or obese patients in Kerman
por: Nakhaee, Akram, et al.
Publicado: (2013)

Evaluation of the pharmacokinetics of metformin and acarbose in the common marmoset
por: Fernandez, Elizabeth, et al.
Publicado: (2019)

Acarbose improved survival for Apc(+/Min) mice
por: Dodds, Sherry G., et al.
Publicado: (2020)

Evaluation of the Bioequivalence of Acarbose in Healthy Chinese People
por: Chen, Yan, et al.
Publicado: (2021)

Complete biosynthetic pathway to the antidiabetic drug acarbose
por: Tsunoda, Takeshi, et al.
Publicado: (2022)

Clinical and economic considerations of antiobesity treatment: a review of orlistat
por: Zohrabian, Armineh
Publicado: (2010)

Mechanism of Orlistat Hydrolysis by the Thioesterase of Human Fatty Acid Synthase
por: Fako, Valerie E., et al.
Publicado: (2014)

An Unexpected Result of Obesity Treatment: Orlistat-Related Acute Pancreatitis
por: Kose, Murat, et al.
Publicado: (2015)

The Application of Quantitative (1)H-NMR for the Determination of Orlistat in Tablets
por: Sun, Shanshan, et al.
Publicado: (2017)

Efficacy and Safety of Lipase Inhibitor Orlistat in Japanese with Excessive Visceral Fat Accumulation: 24-Week, Double-Blind, Randomized, Placebo-Controlled Study
por: Shirai, Kohji, et al.
Publicado: (2018)

Safety and efficacy of acarbose in the treatment of diabetes in Chinese patients
por: He, Ke, et al.
Publicado: (2014)

Insulin Glargine and Acarbose in the treatment of elderly patients with diabetes
por: Li, Jing, et al.
Publicado: (2019)

Extension of the Life Span by Acarbose: Is It Mediated by the Gut Microbiota?
por: Wu, Baiyun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pq592argu8i2uoeedrlvjmv7it