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Enzyme‐Activatable Chemokine Conjugates for In Vivo Targeting of Tumor‐Associated Macrophages

Increased levels of tumor‐associated macrophages (TAMs) are indicators of poor prognosis in most cancers. Although antibodies and small molecules blocking the recruitment of macrophages to tumors are under evaluation as anticancer therapies, these strategies are not specific for macrophage subpopula...

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Detalles Bibliográficos
Autores principales: Barth, Nicole D., Van Dalen, Floris J., Karmakar, Utsa, Bertolini, Marco, Mendive‐Tapia, Lorena, Kitamura, Takanori, Verdoes, Martijn, Vendrell, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826351/
https://www.ncbi.nlm.nih.gov/pubmed/35993914
http://dx.doi.org/10.1002/anie.202207508