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DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview

BACKGROUND: In clinical oncology, systemic 5‐fluorouracil (5‐FU) and its oral pro‐drugs are used to treat a broad group of solid tumours. Patients with dihydropyrimidine dehydrogenase (DPD) enzyme deficiency are at elevated risk of toxicity if treated with standard doses of 5‐FU. DPYD genotyping and...

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Detalles Bibliográficos
Autores principales:	Paulsen, Niels Herluf, Vojdeman, Fie, Andersen, Stig Ejdrup, Bergmann, Troels K., Ewertz, Marianne, Plomgaard, Peter, Hansen, Morten Rix, Esbech, Peter Skov, Pfeiffer, Per, Qvortrup, Camilla, Damkier, Per
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	MINI REVIEWS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826411/ https://www.ncbi.nlm.nih.gov/pubmed/35997509 http://dx.doi.org/10.1111/bcpt.13782

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