Cargando…

Clot‐targeted magnetic hyperthermia permeabilizes blood clots to make them more susceptible to thrombolysis

BACKGROUND: Thrombolysis is a frontline treatment for stroke, which involves the application of tissue plasminogen activator (tPA) to trigger endogenous clot‐degradation pathways. However, it is only effective within 4.5 h of symptom onset because of clot contraction preventing tPA permeation into t...

Descripción completa

Detalles Bibliográficos
Autores principales: Cabrera, David, Eizadi Sharifabad, Maneea, Ranjbar, Jacob A., Telling, Neil D., Harper, Alan G. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826519/
https://www.ncbi.nlm.nih.gov/pubmed/35950914
http://dx.doi.org/10.1111/jth.15846