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Clot‐targeted magnetic hyperthermia permeabilizes blood clots to make them more susceptible to thrombolysis
BACKGROUND: Thrombolysis is a frontline treatment for stroke, which involves the application of tissue plasminogen activator (tPA) to trigger endogenous clot‐degradation pathways. However, it is only effective within 4.5 h of symptom onset because of clot contraction preventing tPA permeation into t...
Autores principales: | Cabrera, David, Eizadi Sharifabad, Maneea, Ranjbar, Jacob A., Telling, Neil D., Harper, Alan G. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826519/ https://www.ncbi.nlm.nih.gov/pubmed/35950914 http://dx.doi.org/10.1111/jth.15846 |
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