Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancer

BACKGROUND: Combination chemotherapy has contributed to increased survival from Hodgkin disease (HD) and testicular cancer (TC). However, questions concerning the quality of spermatozoa after treatment have arisen. While studies have shown evidence of DNA damage and aneuploidy in spermatozoa years f...

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Detalles Bibliográficos
Autores principales: Chan, Donovan, Oros Klein, Kathleen, Riera-Escamilla, Antoni, Krausz, Csilla, O’Flaherty, Cristian, Chan, Peter, Robaire, Bernard, Trasler, Jacquetta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826600/
https://www.ncbi.nlm.nih.gov/pubmed/36611168
http://dx.doi.org/10.1186/s13148-022-01417-1

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