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Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Identification of the underlying mechanism of HCC progression and exploration of new therapeutic drugs are urgently needed. Here, a compound library consisting of 419 FDA-approved drugs was taken to screen potential anticance...

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Detalles Bibliográficos
Autores principales: Tan, Xiang-Peng, He, Yan, Yang, Jing, Wei, Xian, Fan, You-Long, Zhang, Guo-Geng, Zhu, Yi-Dong, Li, Zheng-Qiu, Liao, Hua-Xin, Qin, Da-Jiang, Guan, Xin-Yuan, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826789/
https://www.ncbi.nlm.nih.gov/pubmed/36617552
http://dx.doi.org/10.1038/s41392-022-01248-9